U2U4C1 · U2U4C1_9ACTN
- ProteinChaperonin GroEL
- GenegroL
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids546 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
Catalytic activity
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 29-32 | ATP (UniProtKB | ChEBI) | |||
Binding site | 86-90 | ATP (UniProtKB | ChEBI) | |||
Binding site | 413 | ATP (UniProtKB | ChEBI) | |||
Binding site | 493 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | capsule | |
Cellular Component | cell surface | |
Cellular Component | GroEL-GroES complex | |
Molecular Function | ATP binding | |
Molecular Function | ATP-dependent protein folding chaperone | |
Molecular Function | isomerase activity | |
Molecular Function | unfolded protein binding | |
Biological Process | chaperone cofactor-dependent protein refolding | |
Biological Process | protein refolding | |
Biological Process | response to heat |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameChaperonin GroEL
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Coriobacteriia > Coriobacteriales > Coriobacteriaceae
Accessions
- Primary accessionU2U4C1
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Interaction
Subunit
Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length546
- Mass (Da)56,884
- Last updated2013-11-13 v1
- MD5 Checksum3BC3FED1221A94B66128B1288344ACA8
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AWUP01000005 EMBL· GenBank· DDBJ | ERL12983.1 EMBL· GenBank· DDBJ | Genomic DNA |