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U2TFL3 · U2TFL3_9ACTN

Function

function

Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.

Features

Showing features for active site, binding site.

144450100150200250300350400
Type
IDPosition(s)Description
Active site100Phosphoserine intermediate
Binding site100Mg2+ (UniProtKB | ChEBI); via phosphate group
Binding site239Mg2+ (UniProtKB | ChEBI)
Binding site241Mg2+ (UniProtKB | ChEBI)
Binding site243Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionmagnesium ion binding
Molecular Functionphosphoglucosamine mutase activity
Molecular Functionphosphomannomutase activity
Biological Processcarbohydrate metabolic process
Biological Processpeptidoglycan biosynthetic process
Biological ProcessUDP-N-acetylglucosamine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoglucosamine mutase
  • EC number

Gene names

    • Name
      glmM
    • ORF names
      HMPREF1248_0085

Organism names

Accessions

  • Primary accession
    U2TFL3

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue100Phosphoserine

Post-translational modification

Activated by phosphorylation.

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-133Alpha-D-phosphohexomutase alpha/beta/alpha
Domain157-252Alpha-D-phosphohexomutase alpha/beta/alpha
Domain256-362Alpha-D-phosphohexomutase alpha/beta/alpha
Domain372-437Alpha-D-phosphohexomutase C-terminal

Sequence similarities

Belongs to the phosphohexose mutase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    444
  • Mass (Da)
    48,159
  • Last updated
    2013-11-13 v1
  • MD5 Checksum
    72C2125B116C1D623D2DA8458329D4E5
MKYFGTDGFRGKANEGLTVEHAFKIGRYIGWYYGLRTGRKARIVVGKDTRRSSYMFEYAIASGLVASGADGYLLHVTPTPSVSYVVIDGGFDCGIMITASHNPYQDNGIKLVNRDGFKMEPEILEKVEEYIDGKIEVPLATGDAIGRTIDHEAGRERYLNHLVATANFRLDGMKIGLDCANGASWTVAERVFTTLGAEVHVISDTPNGFNINVNCGSTHISTLQDHVRGNLLDCGFAFDGDADRCIAVDERGEVVDGDLTLFLCGKYLDELGKLPDHMIVATVMSNLGFFKACEANGLKTTQTAVGDKYVHACMRENGYKLGGEQSGHVIFSDYEVTGDGIMTALRILEVMVKKNKPLSELTAPVTIFPQALVNVAVSDKEHALNHDSVKTAIAGVEAKLKGNGRLLVRPSGTEQLVRVMAEAPTQRECEEAVAPVVEALKALG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AWUP01000017
EMBL· GenBank· DDBJ
ERL11824.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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