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U2TFI1 · U2TFI1_9ACTN

Function

function

Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for binding site.

154150100150200250300350400450500
TypeIDPosition(s)Description
Binding site132Zn2+ (UniProtKB | ChEBI)
Binding site159Zn2+ (UniProtKB | ChEBI)
Binding site162Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmethionine-tRNA ligase activity
Biological Processmethionyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Methionine--tRNA ligase
  • EC number
  • Alternative names
    • Methionyl-tRNA synthetase
      (MetRS
      )

Gene names

    • Name
      metG
    • ORF names
      HMPREF1248_0129

Organism names

Accessions

  • Primary accession
    U2TFI1

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain, motif.

Type
IDPosition(s)Description
Domain11-383Methionyl/Leucyl tRNA synthetase
Motif320-324'KMSKS' region
Domain401-538Methionyl-tRNA synthetase anticodon-binding

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    541
  • Mass (Da)
    61,254
  • Last updated
    2013-11-13 v1
  • MD5 Checksum
    8D75F3781AD2689C6A8A4450190E1190
MADNLNKPSFYITTPIYYVNAAPHLGTAYCTILSDVQARYRRAAGYDVKFLTGLDEHGEKVETTAAEHKMTPQEWCDSLAPAFTDIWKTLEISNDDFIRTTEPRQERAVQYLWERMRESGYIYKGSYDGWYCVPEETYFTETQVRHSDEENHTEGQHLCPDCGRMLQRVQEESWFFKLSAFQDRLLAFYDEHPDFVMPSFRMKEVRTFVEGGLQDLSVSRTSFDWGIKLPFDEKHVTYVWFDALLNYMTAVGYGQPGEDAAVNLARRWPAQYHVVGKDIIRFHCVIWPAMLMAIGEALPEHVFAHGFLMVRNEETGQGEKMSKSRGNAIAPQEVIDLLGIEGYRYYFMRDCKPGEDGAISFARMEQVYNADLANSWGNLVSRALNMSVKYFDGKTPALPADWAQRESPLTQVAAGIYQRYAAKMDVMAYPEAIDEVMALVGAANHYIEDSKPWALAKPDENGVAQLDELSFVIGGLLEAIRISAHLLAPFMPKTSSEVLRRLSLGDEAESDDLAAVCAWGQLPSGIAVEKGEALFPRLASK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AWUP01000017
EMBL· GenBank· DDBJ
ERL11779.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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