S8C072 · S8C072_9LAMI

  • Protein
    DNA-(apurinic or apyrimidinic site) endonuclease 2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Probably binds two magnesium or manganese ions per subunit.
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Features

Showing features for binding site, active site, site.

160850100150200250300350400450500550600
TypeIDPosition(s)Description
Binding site7Mg2+ 1 (UniProtKB | ChEBI)
Binding site37Mg2+ 1 (UniProtKB | ChEBI)
Active site153
Active site194Proton donor/acceptor
Binding site194Mg2+ 1 (UniProtKB | ChEBI)
Binding site196Mg2+ 1 (UniProtKB | ChEBI)
Site196Transition state stabilizer
Site265Important for catalytic activity
Binding site322Mg2+ 1 (UniProtKB | ChEBI)
Active site323Proton acceptor
Binding site323Mg2+ 1 (UniProtKB | ChEBI)
Site323Interaction with DNA substrate

GO annotations

AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA-(apurinic or apyrimidinic site) endonuclease activity
Molecular Functiondouble-stranded DNA 3'-5' DNA exonuclease activity
Molecular Functionphosphoric diester hydrolase activity
Molecular Functionzinc ion binding
Biological Processbase-excision repair

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    DNA-(apurinic or apyrimidinic site) endonuclease 2

Gene names

    • ORF names
      M569_14760

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > lamiids > Lamiales > Lentibulariaceae > Genlisea

Accessions

  • Primary accession
    S8C072

Proteomes

Subcellular Location

Keywords

  • Cellular component

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region514-535Disordered
Domain556-605GRF-type

Sequence similarities

Belongs to the DNA repair enzymes AP/ExoA family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    608
  • Mass (Da)
    68,187
  • Last updated
    2013-10-16 v1
  • Checksum
    0296E2DA71D15F98
MKIVTYNVNGLRGRVAQFGSLRKLLDAFDADVICFQETKLSRSELRADLVQAEGYESFFSCTRTSDKGRTGYSGVATFCRVKSAFASDEVALPVSAEEGFAGKLSHSSGLGKSDCPSLLRGLESFSVEDVLKADSEGRCVMTDHRHFVLINVYGPRAGHDDLERVQFKRCFFYILQKRWESLLDQGRRVIVVGDLNIAPSAIDRCDAAPDFEKNEFRVWFRSLLMKNGGSFFDAFREKHPDRREAYTCWPTNSGAEEFNFGSRIDHILCAGSCLHKEENQAHNFMLCHVKDCDILQQFKRWKPGDAPRHSIKARNVKLEGSDHAPVYMSLVGMPNVEQHNTPPLSMRYCPQVYGYQQTLVTMFSRKQAAEGISSRGETTSISENCAVRKCSQICKRDSCCESTADFCSEEVPFASVGSYDESQLHMLSSSHLPETDHPELVPSRTCEKKAKRNQWSQLSVKSFFHKKVCVGAESNNLRSDNELEHGEASISNFESDEAVGDNCRHFGTHEWQPENNIPVQEDGGNPPQSAGKQKNNTALVEWQRIQQLMQSSVPLCKGHQEPCVPRVVKKPGVNFGRRFYTCARAEGPASNPEANCGFFKWAAAKSIK

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue608

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AUSU01007870
EMBL· GenBank· DDBJ
EPS60044.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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