Q9ZSK1 · GTOMC_ARATH

Function

function

Involved in the synthesis of tocopherol (vitamin E). Methylates gamma- and delta-tocopherol to form beta- and alpha-tocopherol, respectively.

Miscellaneous

Seeds overexpressing VTE4 show increased levels of alpha-tocopherol.

Catalytic activity

Pathway

Cofactor biosynthesis; tocopherol biosynthesis.

GO annotations

AspectTerm
Cellular Componentchloroplast
Cellular Componentnucleus
Molecular FunctionS-adenosylmethionine-dependent methyltransferase activity
Molecular Functiontocopherol C-methyltransferase activity
Biological Processmethylation
Biological Processvitamin E biosynthetic process

Keywords

Enzyme and pathway databases

Chemistry

Names & Taxonomy

Protein names

  • Recommended name
    Tocopherol O-methyltransferase, chloroplastic
  • EC number
  • Alternative names
    • Gamma-tocopherol methyltransferase
    • Vitamin E pathway gene 4 protein (AtVTE4)

Gene names

    • Name
      VTE4
    • Synonyms
      G-TMT
    • ORF names
      F13O11.27
    • Ordered locus names
      At1g64970

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q9ZSK1
  • Secondary accessions
    • Q9XIP9

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

Phenotypes & Variants

Disruption phenotype

Slight reduction of fresh weight in mature plants. Leaves with high levels of gamma-tocopherol and absence of alpha-tocopherol.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 47 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for transit peptide, modified residue, chain.

Type
IDPosition(s)Description
Transit peptide1-51Chloroplast
Modified residue52N-acetylalanine
ChainPRO_000001867752-348Tocopherol O-methyltransferase, chloroplastic

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region130-139SAM motif I
Region193-201SAM motif II
Region220-229SAM motif III

Sequence similarities

Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    348
  • Mass (Da)
    38,075
  • Last updated
    2005-05-10 v2
  • MD5 Checksum
    4B81648DFAB82D82CCC96F6AE0B49E05
MKATLAAPSSLTSLPYRTNSSFGSKSSLLFRSPSSSSSVSMTTTRGNVAVAAAATSTEALRKGIAEFYNETSGLWEEIWGDHMHHGFYDPDSSVQLSDSGHKEAQIRMIEESLRFAGVTDEEEEKKIKKVVDVGCGIGGSSRYLASKFGAECIGITLSPVQAKRANDLAAAQSLAHKASFQVADALDQPFEDGKFDLVWSMESGEHMPDKAKFVKELVRVAAPGGRIIIVTWCHRNLSAGEEALQPWEQNILDKICKTFYLPAWCSTDDYVNLLQSHSLQDIKCADWSENVAPFWPAVIRTALTWKGLVSLLRSGMKSIKGALTMPLMIEGYKKGVIKFGIITCQKPL

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict175in Ref. 1; AAD02882 and 5; AAM64696
Sequence conflict188in Ref. 5; AAM64696

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF104220
EMBL· GenBank· DDBJ
AAD02882.1
EMBL· GenBank· DDBJ
mRNA
AC006193
EMBL· GenBank· DDBJ
AAD38271.2
EMBL· GenBank· DDBJ
Genomic DNA
CP002684
EMBL· GenBank· DDBJ
AEE34310.1
EMBL· GenBank· DDBJ
Genomic DNA
AY049258
EMBL· GenBank· DDBJ
AAK83600.1
EMBL· GenBank· DDBJ
mRNA
AY090280
EMBL· GenBank· DDBJ
AAL90941.1
EMBL· GenBank· DDBJ
mRNA
AY087138
EMBL· GenBank· DDBJ
AAM64696.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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