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Q8ZHG8 · SPEA_YERPE

  • Protein
    Biosynthetic arginine decarboxylase
  • Gene
    speA
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the biosynthesis of agmatine from arginine.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site308-318substrate

GO annotations

AspectTerm
Molecular Functionarginine decarboxylase activity
Molecular Functionmetal ion binding
Biological Processarginine catabolic process
Biological Processputrescine biosynthetic process from arginine
Biological Processspermidine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Biosynthetic arginine decarboxylase
  • EC number
  • Short names
    ADC

Gene names

    • Name
      speA
    • Ordered locus names
      YPO0929, y3313, YP_3513

Organism names

  • Taxonomic identifier
  • Strains
    • CO-92 / Biovar Orientalis
    • KIM10+ / Biovar Mediaevalis
    • 91001 / Biovar Mediaevalis
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Yersiniaceae > Yersinia

Accessions

  • Primary accession
    Q8ZHG8
  • Secondary accessions
    • Q0WIB1

Proteomes

PTM/Processing

Features

Showing features for chain, modified residue.

Type
IDPosition(s)Description
ChainPRO_00001499911-659Biosynthetic arginine decarboxylase
Modified residue128N6-(pyridoxal phosphate)lysine

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    659
  • Mass (Da)
    74,104
  • Last updated
    2002-03-01 v1
  • MD5 Checksum
    41FD499B90841D9ABB5743182AD28B98
MSDDNLISRPLTAGAHVSLRSMQEVAMNDRNASKMLSTYNVAYWGGNYYDVNELGHISVCPDPDIREARVDLAQLVKKMQLEQGQRLPALFCFPQILQHRLRSINAAFKRARESFGYEGGYFLVYPIKVNQHRRVIESLVNSGEPLGLEAGSKAEMMAVLAHAGMTRSVIVCNGYKDREYIRLALIGEKLGHKVYLVIEKMSEIKMVLEEAERLNVVPRLGVRARLASQGSGKWQASGGEKSKFGLSATQVLQLVDMLREANSLESLQLLHFHLGSQLSNIRDISTGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNEYANNVIWGIGDACNEHGLPHPTVITESGRAVTAHHTVLVSNVIGVERNEFCEPQPPEAGAPRALESLWDTWQEMQEPENRRSLREWLHDSQMDLHDVHTQYAHGMLDLTHRAWAEQLYLSICNEIQKQLDPSNRAHRPIIDELQERMADKLYVNFSLFQSMPDAWGIDQLFPVLPLEGLDKPPERRAVLLDITCDSDGTIDHYIDGDGVATTMPMPPYDPENPPLLGFFMVGAYQEILGNMHNLFGDTAAVDVYVFPDGTVEVEQTDEGDTVADMLEYVQLNPEKLLEHFRGQVKETDLDTELQAQFLEEFEAGLYGYTYLEDE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL590842
EMBL· GenBank· DDBJ
CAL19596.1
EMBL· GenBank· DDBJ
Genomic DNA
AE009952
EMBL· GenBank· DDBJ
AAM86863.1
EMBL· GenBank· DDBJ
Genomic DNA
AE017042
EMBL· GenBank· DDBJ
AAS63667.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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