Q8X7H7 · YEGS_ECO57
- ProteinProbable lipid kinase YegS
- GeneyegS
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids299 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Probably phosphorylates lipids; the in vivo substrate is unknown.
Cofactor
Ca2+ (UniProtKB | Rhea| CHEBI:29108 )
Note: Binds 1 Mg2+ ion per subunit. Ca2+ may be able to substitute.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 40 | ATP (UniProtKB | ChEBI) | |||
Binding site | 66-72 | ATP (UniProtKB | ChEBI) | |||
Binding site | 95 | ATP (UniProtKB | ChEBI) | |||
Binding site | 215 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 218 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 220 | Mg2+ (UniProtKB | ChEBI) | |||
Active site | 271 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | lipid kinase activity | |
Molecular Function | magnesium ion binding | |
Biological Process | phospholipid biosynthetic process | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProbable lipid kinase YegS
- EC number
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia
Accessions
- Primary accessionQ8X7H7
- Secondary accessions
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000292143 | 1-299 | Probable lipid kinase YegS | ||
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 2-133 | DAGKc | |||
Sequence similarities
Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length299
- Mass (Da)31,988
- Last updated2002-03-01 v1
- ChecksumFC4A1C427832552F
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE005174 EMBL· GenBank· DDBJ | AAG57146.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BA000007 EMBL· GenBank· DDBJ | BAB36315.1 EMBL· GenBank· DDBJ | Genomic DNA |