Q6E7H0 · ORC3_ARATH

Function

function

Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnuclear origin of replication recognition complex
Cellular Componentorigin recognition complex
Molecular FunctionDNA binding
Biological ProcessDNA replication
Biological Processlateral root development
Biological Processresponse to sucrose

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Origin of replication complex subunit 3
  • Short names
    AtORC3

Gene names

    • Name
      ORC3
    • ORF names
      F5E19.30
    • Ordered locus names
      At5g16690

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q6E7H0
  • Secondary accessions
    • Q9LFE8

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004314311-734Origin of replication complex subunit 3

Proteomic databases

PTM databases

Expression

Tissue specificity

Follow a cell-cycle regulation with a peak at the G1/S-phase (PubMed:16179646).
Mostly expressed in siliques and flowers, and, to a lower exent, in flower buds, leaves, roots and stems (PubMed:15358564, PubMed:16179646).

Induction

Regulated by E2F (PubMed:16126853, PubMed:16179646).
Accumulates rapidly after cell cycle reactivation by sucrose addition following cell cycle arrest mediated by sucrose deprivation (PubMed:15358564, PubMed:16179646).

Gene expression databases

Interaction

Subunit

Component of the origin recognition complex (ORC) composed of at least ORC1 (ORC1A or ORC1B), ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle and development dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase. Interacts directly with ORC1A, ORC2, ORC4, ORC5 and ORC6.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias.

Type
IDPosition(s)Description
Region1-25Disordered
Compositional bias8-25Polar residues
Region532-554Disordered

Sequence similarities

Belongs to the ORC3 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    734
  • Mass (Da)
    82,755
  • Last updated
    2004-08-16 v1
  • MD5 Checksum
    F4869ED2732EC1ED625AEDB56CAD7E4E
MAPSGTVADPPQCSTTDSFNSSDTAENDIRPFFVLHKASSGNHNGKLTGIVKSKRRIESPSPKIAKRSEVESVEEEDGQFFSTLRFKVFETVWSKIEKTIEDVLRNSNSKVFSGIHDWIRESFESIISSGALKLSEAVRSYPVLTQASSKQLLTAMVLTRNLEMVDDLLTFEELELHLKSQGCHVAKLSSMDFSAKSGVGGCLRGLLRQFVMPTVDVADVTILASWYRENKNHENPVVIIVDDTERCCGPVLSDLILILSEWAIKVPIFLIMGVSTAHDAPRKILSVNALQRLCATRFTLSSPAERMDAVLKAVFLKPCSGFTVSHKVALFMRSYFLCQDGTLTSFVRTLKIACLQHFSLEPLSIMLEHFCHDGVNQLSGEGTELLTEATMKHAFDLPSVTRNKITRSTFEMLPHFLLDLQRMPNPWSIVVLCLYEAGKFDKLRLLDIFCEILDPEARYLKYFSPSEIVNSQSHNSGRNNVIRRVLRKLRDLSPSQLSSMLKSWENLTAEFTEINDKVIELHPFMRAVEAAGQRQGLPNSPKKHASRSNSKLEKELKAMTDKVATVIEFMLREYMKPVESVPFHEILCFKNVDKLQSALLGDPRGRIQLDLLESHDILHCVCCSQRGTTLLPSMHDTSILYKLAQEHADVINLHDWYQSFKTILIPRSSKAKQKSKSSSKSKKRKEICEEPEAPAEALIQARFCRAVMELQITGLIRMPSKRRPDFVQRVAFGS

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A1P8BC82A0A1P8BC82_ARATHORC3710

Sequence caution

The sequence CAC01833.1 differs from that shown. Reason: Erroneous gene model prediction

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias8-25Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY524002
EMBL· GenBank· DDBJ
AAT37463.1
EMBL· GenBank· DDBJ
mRNA
AL391147
EMBL· GenBank· DDBJ
CAC01833.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
CP002688
EMBL· GenBank· DDBJ
AED92326.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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