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Q5KSN5 · ECDPS_STREO

Function

function

Involved in viguiepinol biosynthesis. Catalyzes the conversion of geranylgeranyl diphosphate (GGDP) into copalyl diphosphate (ent-CDP).

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Note: Activity is highest with Mg2+. Can also use Zn2+, Co2+, Mn2+ and Ni2+.

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
13.7 μMGGDP
kcat is 0.033 sec-1.

pH Dependence

Optimum pH is 5.5.

Temperature Dependence

Optimum temperature is 35 degrees Celsius.

Pathway

Antibiotic biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site291a divalent metal cation (UniProtKB | ChEBI)
Binding site293a divalent metal cation (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionent-copalyl diphosphate synthase activity
Molecular Functionmagnesium ion binding
Molecular Functionterpene synthase activity
Biological Processantibiotic biosynthetic process
Biological Processditerpenoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ent-copalyl diphosphate synthase
  • EC number
  • Short names
    Ent-CDP synthase

Gene names

    • Name
      ent-cdps

Organism names

Accessions

  • Primary accession
    Q5KSN5

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004316971-511Ent-copalyl diphosphate synthase

Interaction

Subunit

Homodimer.

Structure

Family & Domains

Features

Showing features for motif.

TypeIDPosition(s)Description
Motif291-294DXDD motif

Sequence similarities

Belongs to the terpene synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    511
  • Mass (Da)
    54,768
  • Last updated
    2005-02-15 v1
  • MD5 Checksum
    4A1195E8D3C8FFE035D00AB0867E7EF9
MNVTSFAALRAAAQDIVDEMIADPYGLTSPSVYETARMVVSAPWLEGHRQRVEFLLAQQHEDGTWGGPAAYGLLPTLSAVDALLSVAGTQDARRVAGAVESGLAALAGRFPRNVELPDTIAVELLVPWLIEQVDQRLSRMDDRGDLPGRLDLQADTGTLSGIRELLRQNTGIPEKTWHSLEALGAPAVRSGTVTPMGGAVGASPAATSAWLGDPPHTDAAKACLAYLHQTQARHGGPVSGITSISYFELAWVVTALSGSGLDVDIPAQVPDILRTALGANGLSAGPGLPADSDDTSAALHALDLLGKPESVDCLWEYDTGLYFTCFPKERTPSTSTNAHILVALADRRGQGDTRYDHAAERVGGWLVEQQQPDGRWMDKWHASPYYATACGAAAMARLDGPRTSAALDDAIRWVLDTQHADGSWGRWEGTGEETAYALQVLNHRAAPDRPALEAIRAGRAFLSGHVEDDRRNPPLWHDKDLYTPVRVIRAEILGTLAATQRLAEAEKEARA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB183750
EMBL· GenBank· DDBJ
BAD86797.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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