Q58DQ3 · RL6_BOVIN

  • Protein
    Large ribosomal subunit protein eL6
  • Gene
    RPL6
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

function

Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosolic large ribosomal subunit
Cellular Componentorganelle membrane
Cellular Componentrough endoplasmic reticulum
Molecular FunctionRNA binding
Molecular Functionstructural constituent of ribosome
Biological Processcytoplasmic translation
Biological Processribosomal large subunit assembly

Keywords

Enzyme and pathway databases

    • R-BTA-156827L13a-mediated translational silencing of Ceruloplasmin expression
    • R-BTA-1799339SRP-dependent cotranslational protein targeting to membrane
    • R-BTA-6791226Major pathway of rRNA processing in the nucleolus and cytosol
    • R-BTA-72689Formation of a pool of free 40S subunits
    • R-BTA-72706GTP hydrolysis and joining of the 60S ribosomal subunit

Names & Taxonomy

Protein names

  • Recommended name
    Large ribosomal subunit protein eL6
  • Alternative names
    • 60S ribosomal protein L6

Gene names

    • Name
      RPL6

Organism names

  • Taxonomic identifier
  • Strain
    • Hereford
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    Q58DQ3
  • Secondary accessions
    • A3KMZ3

Proteomes

Organism-specific databases

Subcellular Location

Cytoplasm, cytosol
Cytoplasm
Note: Detected on cytosolic polysomes (By similarity).
Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).

Keywords

PTM/Processing

Features

Showing features for chain, cross-link, modified residue.

Type
IDPosition(s)Description
ChainPRO_00001710071-287Large ribosomal subunit protein eL6
Cross-link5Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
Modified residue93N6-succinyllysine
Modified residue126Phosphoserine
Modified residue206N6-succinyllysine
Modified residue238N6-acetyllysine

Keywords

Proteomic databases

Expression

Gene expression databases

Interaction

Subunit

Component of the large ribosomal subunit (By similarity).
May bind IPO9 with low affinity (By similarity).

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for compositional bias, region.

Type
IDPosition(s)Description
Compositional bias1-29Basic and acidic residues
Region1-44Disordered
Compositional bias30-44Basic residues

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    287
  • Mass (Da)
    32,690
  • Last updated
    2007-01-23 v3
  • Checksum
    D3546817AB51C143
MAGEKAEKPDTKEKKPEAKKADAGKKAKKVEKVKKVKKGKPHCSRNPVLVRGIGRYSRSAMYSRKALYKRKYSAAKSKVEKKKKVRVLATVTKPVGGDKNGGTRVVKLRKMPRYYPTEDVPRKLLSHGKKPFSKHVRKLRASITPGTILIILTGRHRGKRVVFLKQLGSGLLLVTGPLSLNRVPLRRTHQKFVIATSTKIDISGVKIPEHLTDTYFKKKKLRKPRHQEGEIFDTEREKYEITEQRKVDQKAVDSQILRRIKAVPQLQGYLRSVFALTNGIYPHKVVF

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-29Basic and acidic residues
Compositional bias30-44Basic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BT021543
EMBL· GenBank· DDBJ
AAX46390.1
EMBL· GenBank· DDBJ
mRNA
BT021544
EMBL· GenBank· DDBJ
AAX46391.1
EMBL· GenBank· DDBJ
mRNA
AY911360
EMBL· GenBank· DDBJ
AAW82124.1
EMBL· GenBank· DDBJ
mRNA
BC133430
EMBL· GenBank· DDBJ
AAI33431.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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