Q39033 · PLCD2_ARATH

Function

function

The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. At physiological calcium concentration, the preferred substrate is phosphatidylinositol 4,5-bisphosphate versus phosphatidylinositol.

Catalytic activity

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Features

Showing features for active site.

158150100150200250300350400450500550
TypeIDPosition(s)Description
Active site118
Active site164

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionphosphatidylinositol phospholipase C activity
Molecular Functionphospholipase C activity
Biological Processdefense response to bacterium
Biological Processembryo sac development
Biological Processfloral organ development
Biological Processintracellular signal transduction
Biological Processlipid catabolic process
Biological Processmicrosporogenesis
Biological Processpositive regulation of auxin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoinositide phospholipase C 2
  • EC number
  • Alternative names
    • Phosphoinositide phospholipase PLC2 (AtPLC2; PI-PLC2)

Gene names

    • Name
      PLC2
    • ORF names
      T8G24.4
    • Ordered locus names
      At3g08510

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q39033
  • Secondary accessions
    • Q56XL3
    • Q8LG47

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Cell membrane
; Peripheral membrane protein

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003241271-581Phosphoinositide phospholipase C 2

Post-translational modification

Phosphorylation level varies significantly during early response to bacterial elicitor.

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed in roots, shoots, leaves and flowers.

Induction

Not induced by environmental stresses such as dehydration, salinity and low temperature.

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain26-102EF-hand-like
Domain103-248PI-PLC X-box
Region279-314Disordered
Domain317-433PI-PLC Y-box
Domain434-563C2

Domain

Amino acids 23-36 of the EF-hand-like domain are necessary catalysis but not for binding to lipid vesicles.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete

This entry describes 1 isoforms produced by Alternative splicing. A number of isoforms are produced. According to EST sequences.

Q39033-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    581
  • Mass (Da)
    66,122
  • Last updated
    1996-11-01 v1
  • Checksum
    E337EB95EC16FC0B
MSKQTYKVCFCFRRRFRYTASEAPREIKTIFEKYSENGVMTVDHLHRFLIDVQKQDKATREDAQSIINSASSLLHRNGLHLDAFFKYLFGDNNPPLALHKVHHDMDAPISHYFIFTGHNSYLTGNQLSSDCSEVPIIDALKKGVRVIELDIWPNSNKDDIDVLHGMTLTTPVGLIKCLKAIRAHAFDVSDYPVVVTLEDHLTPDLQSKVAEMVTEIFGEILFTPPVGESLKEFPSPNSLKRRIIISTKPPKEYKEGKDVEVVQKGKDLGDEEVWGREVPSFIQRNKSEAKDDLDGNDDDDDDDDEDKSKINAPPQYKHLIAIHAGKPKGGITECLKVDPDKVRRLSLSEEQLEKAAEKYAKQIVRFTQHNLLRIYPKGTRVTSSNYNPLVGWSHGAQMVAFNMQGYGRSLWLMQGMFRANGGCGYIKKPDLLLKSGSDSDIFDPKATLPVKTTLRVTVYMGEGWYFDFRHTHFDQYSPPDFYTRVGIAGVPGDTVMKKTKTLEDNWIPAWDEVFEFPLTVPELALLRLEVHEYDMSEKDDFGGQTCLPVWELSEGIRAFPLHSRKGEKYKSVKLLVKVEFV

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
F4IX90F4IX90_ARATHPLC2552

Sequence caution

The sequence AAM61037.1 differs from that shown. Reason: Erroneous termination Truncated C-terminus.

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
D50804
EMBL· GenBank· DDBJ
BAA09432.1
EMBL· GenBank· DDBJ
mRNA
AC074395
EMBL· GenBank· DDBJ
AAG50827.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002686
EMBL· GenBank· DDBJ
AEE74640.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002686
EMBL· GenBank· DDBJ
AEE74641.1
EMBL· GenBank· DDBJ
Genomic DNA
AF360206
EMBL· GenBank· DDBJ
AAK25916.1
EMBL· GenBank· DDBJ
mRNA
AY040054
EMBL· GenBank· DDBJ
AAK64112.1
EMBL· GenBank· DDBJ
mRNA
AY084465
EMBL· GenBank· DDBJ
AAM61037.1
EMBL· GenBank· DDBJ
mRNA Sequence problems.
AK221660
EMBL· GenBank· DDBJ
BAD95335.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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