P45860 · CLS1_BACSU

Function

function

Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity).
May have a role in the heat shock response since the level of the transcript of ywiE increases after a heat shock

Catalytic activity

Features

Showing features for active site.

150050100150200250300350400450500
TypeIDPosition(s)Description
Active site242
Active site244
Active site249
Active site418
Active site420
Active site425

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functioncardiolipin synthase activity
Biological Processcardiolipin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable cardiolipin synthase YwiE
  • EC number
  • Short names
    CL synthase 1

Gene names

    • Name
      ywiE
    • Ordered locus names
      BSU37240

Organism names

Accessions

  • Primary accession
    P45860

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-26Helical
Transmembrane31-51Helical
Transmembrane59-79Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002012471-500Probable cardiolipin synthase YwiE

Proteomic databases

Expression

Induction

By heat shock.

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain237-264PLD phosphodiesterase 1
Domain413-440PLD phosphodiesterase 2

Sequence similarities

Belongs to the phospholipase D family. Cardiolipin synthase subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    500
  • Mass (Da)
    58,248
  • Last updated
    1995-11-01 v1
  • Checksum
    3BEF85FD4F0681B8
MLKRRLEFFFLYMMLIGAYVIWFFPVSRLEFYGGLLCYISIILFSIYSLILENRTSQHTLLWIHILVFFPIVGYVFYLFSGQLYVKGKLFKTKRMYNREKLRKLFDKEETPEVTGLKDNQERFFTYSIRAAHMNINTKSNIKVLKNGEETFPDIFKAMRKAESYIHIEYYMFKSDMLGRGMMDIMMEKARQGVEVRFLYDAAGSMKLARRDIMRMKQAGVDIVPFSPLKYGFFNQKLNFRNHRKIVIIDGKTGFVGGLNVGKEYISRDPYIGFWRDTHLRLEGEIVQTLHAIFMLDWEYVSNEVLIDQEEYNTPVPVEGGGIYQIVATGPDMKESMSDLYYEMISSAQKSIWIATPYFVPNESIRTALKAAATKGVEVRVMVPEKNDSFLTQYASRSYFPELLLEGIEVYSYQKGFMHQKVMIIDGDLASVGTANMDMRSFQLNFEVNVFFTDAEAIRTLEAHFEEDMQESEKLSPVGFYKRGVADRTKESFARLFSGVL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
Z49884
EMBL· GenBank· DDBJ
CAA90049.1
EMBL· GenBank· DDBJ
Genomic DNA
Z49782
EMBL· GenBank· DDBJ
CAA89861.1
EMBL· GenBank· DDBJ
Genomic DNA
AL009126
EMBL· GenBank· DDBJ
CAB15752.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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