P15109 · PCXA_BURCE
- ProteinProtocatechuate 3,4-dioxygenase alpha chain
- GenepcaG
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids197 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Plays an essential role in the utilization of numerous aromatic and hydroaromatic compounds via the beta-ketoadipate pathway.
Catalytic activity
- 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate + 2 H+
Cofactor
Note: Binds Fe3+ ion per subunit.
Pathway
Aromatic compound metabolism; beta-ketoadipate pathway; 3-carboxy-cis,cis-muconate from 3,4-dihydroxybenzoate: step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 130 | 3,4-dihydroxybenzoate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ferric iron binding | |
Molecular Function | protocatechuate 3,4-dioxygenase activity | |
Biological Process | beta-ketoadipate pathway |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProtocatechuate 3,4-dioxygenase alpha chain
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Burkholderia > Burkholderia cepacia complex
Accessions
- Primary accessionP15109
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000085096 | 1-197 | Protocatechuate 3,4-dioxygenase alpha chain | ||
Interaction
Subunit
The enzyme is an oligomer of 12 copies of the alpha and beta chains.
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length197
- Mass (Da)21,394
- Last updated1990-04-01 v1
- MD5 ChecksumE297B464A0F3BCEC3F243D31A6F13D0F
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
M30791 EMBL· GenBank· DDBJ | AAA25925.1 EMBL· GenBank· DDBJ | Genomic DNA |