N1NWH7 · N1NWH7_YEASC
- ProteinCasein kinase II subunit alpha
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids339 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
Catalytic activity
- L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 79 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | nucleus | |
Cellular Component | protein kinase CK2 complex | |
Molecular Function | ATP binding | |
Molecular Function | protein serine kinase activity | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | DNA damage response | |
Biological Process | peptidyl-serine phosphorylation | |
Biological Process | peptidyl-threonine phosphorylation | |
Biological Process | regulation of cell cycle | |
Biological Process | regulation of transcription by RNA polymerase I | |
Biological Process | regulation of transcription by RNA polymerase III |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCasein kinase II subunit alpha
- EC number
- Short namesCK II alpha
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Saccharomycetaceae > Saccharomyces
Accessions
- Primary accessionN1NWH7
Proteomes
Subcellular Location
Interaction
Subunit
Heterotetramer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 50-334 | Protein kinase | |||
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length339
- Mass (Da)39,404
- Last updated2013-06-26 v1
- MD5 ChecksumC022A4CEE1A85400226316BB820A1E1C
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CM001536 EMBL· GenBank· DDBJ | EIW07493.1 EMBL· GenBank· DDBJ | Genomic DNA |