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M1WRF9 · M1WRF9_PSEP2

Function

function

Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site48
Active site338Nucleophile

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionL-methionine:thioredoxin-disulfide S-oxidoreductase activity
Molecular Functionpeptide-methionine (R)-S-oxide reductase activity
Molecular Functionpeptide-methionine (S)-S-oxide reductase activity
Biological Processprotein modification process
Biological Processprotein repair
Biological Processresponse to oxidative stress

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Multifunctional fusion protein

Including 2 domains:

  • Recommended name
    Peptide methionine sulfoxide reductase MsrA
  • EC number
  • Short names
    Protein-methionine-S-oxide reductase
  • Alternative names
    • Peptide-methionine (S)-S-oxide reductase
      (Peptide Met(O) reductase
      )
  • Recommended name
    Peptide methionine sulfoxide reductase MsrB
  • EC number
  • Alternative names
    • Peptide-methionine (R)-S-oxide reductase

Gene names

    • Name
      msrAB
    • Synonyms
      msrA
      , msrB
    • Ordered locus names
      BN4_11045

Organism names

Accessions

  • Primary accession
    M1WRF9

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-26
ChainPRO_500401943627-368Multifunctional fusion protein

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain227-349MsrB

Sequence similarities

Belongs to the MsrA Met sulfoxide reductase family.
Belongs to the MsrB Met sulfoxide reductase family.
In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    368
  • Mass (Da)
    41,284
  • Last updated
    2013-05-01 v1
  • MD5 Checksum
    A091E89BC6EF920ECCE1DE101BD2AE5C
MSLKAYCISLAGVALLLVALAHTGYAAEKETSMTETKKLESATVAGGCFWCVESDMEKLPGVVKVVSGYAGGEEVNPSYEQVSSGTTGHREAVQISFDPTLVTYREVIDYFWKHFDPTDAGGSFGDRGAQYTSAIFYHDESQRRDAEASKEALDASGRLGKPVVTPLIPLTSFYEAEAYHQDYYKKSPARYKTYQYFSGRDKYVNKTWGKNAGKSAPEKGSFVKPDDETLRRLLTEVQYDVTQNKGTEPPFENEYWDNKAEGLYVDRVSGEPLFSSRDKYKSGTGWPSFTRPLVADNIVEKQDRSFFSVRTEIRSRMGDSHLGHVFDDGPPPTGLRYCMNSAALRFVPKDELEKEGYGEFLPLFEERK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FO203427
EMBL· GenBank· DDBJ
CCH48282.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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