K7FQ96 · K7FQ96_PELSI
- Protein1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
- GenePLCB1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1073 (go to sequence)
- Protein existencePredicted
- Annotation score5/5
Function
Catalytic activity
- a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 1D-myo-inositol 1-phosphate + a 1,2-diacyl-sn-glycerol + H+This reaction proceeds in the forward direction.
Cofactor
Note: Binds 1 Ca2+ ion per subunit.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 251 | ||||
Binding site | 252 | Ca2+ (UniProtKB | ChEBI) | |||
Binding site | 281 | Ca2+ (UniProtKB | ChEBI) | |||
Binding site | 283 | Ca2+ (UniProtKB | ChEBI) | |||
Active site | 298 | ||||
Binding site | 332 | Ca2+ (UniProtKB | ChEBI) | |||
GO annotations
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Testudinata > Testudines > Cryptodira > Trionychia > Trionychidae > Pelodiscus
Accessions
- Primary accessionK7FQ96
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain, coiled coil.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 387-454 | Disordered | |||
Compositional bias | 400-418 | Polar residues | |||
Compositional bias | 427-442 | Acidic residues | |||
Domain | 461-577 | PI-PLC Y-box | |||
Domain | 577-705 | C2 | |||
Compositional bias | 755-771 | Basic and acidic residues | |||
Region | 755-789 | Disordered | |||
Compositional bias | 887-904 | Basic and acidic residues | |||
Region | 887-910 | Disordered | |||
Coiled coil | 914-942 | ||||
Region | 987-1015 | Disordered | |||
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,073
- Mass (Da)122,877
- Last updated2013-01-09 v1
- MD5 Checksum62F5F1CD76C63DFF5FA7F445233B60FF
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 400-418 | Polar residues | |||
Compositional bias | 427-442 | Acidic residues | |||
Compositional bias | 755-771 | Basic and acidic residues | |||
Compositional bias | 887-904 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AGCU01171819 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AGCU01171820 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AGCU01171821 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AGCU01171822 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AGCU01171823 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AGCU01171824 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AGCU01171825 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AGCU01171826 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AGCU01171827 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AGCU01171828 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |