I2FTP9 · I2FTP9_USTHO
- ProteinCysteine-S-conjugate beta-lyase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids963 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- (R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + H+This reaction proceeds in the forward direction.
Cofactor
Pathway
Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 1/3.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | cysteine-S-conjugate beta-lyase activity | |
Molecular Function | mevalonate kinase activity | |
Molecular Function | pyridoxal phosphate binding | |
Biological Process | 'de novo' L-methionine biosynthetic process | |
Biological Process | isopentenyl diphosphate biosynthetic process, mevalonate pathway | |
Biological Process | phosphorylation | |
Biological Process | transsulfuration |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCysteine-S-conjugate beta-lyase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Ustilaginomycotina > Ustilaginomycetes > Ustilaginales > Ustilaginaceae > Ustilago
Accessions
- Primary accessionI2FTP9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-54 | Disordered | |||
Region | 521-540 | Disordered | |||
Domain | 672-746 | GHMP kinase N-terminal | |||
Domain | 835-901 | GHMP kinase C-terminal | |||
Sequence similarities
Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
Belongs to the trans-sulfuration enzymes family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length963
- Mass (Da)102,486
- Last updated2012-07-11 v1
- MD5 Checksum606A53C1AFD882287CC5C915CFE2473C
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CAGI01000153 EMBL· GenBank· DDBJ | CCF50292.1 EMBL· GenBank· DDBJ | Genomic DNA |