H0ZCF8 · H0ZCF8_TAEGU

Function

Catalytic activity

Features

Showing features for active site, site, binding site.

TypeIDPosition(s)Description
Active site52Proton donor
Site82Lowers pKa of active site Tyr
Binding site115substrate

GO annotations

AspectTerm
Cellular Componentapical plasma membrane
Cellular Componentcytosol
Cellular Componentsynapse
Molecular Functionaldose reductase (NADPH) activity
Molecular Functionglucuronolactone reductase activity
Molecular FunctionL-glucuronate reductase activity
Molecular FunctionS-nitrosoglutathione reductase (NADH) activity
Biological Processaldehyde catabolic process
Biological Processcellular detoxification of aldehyde
Biological ProcessD-glucuronate catabolic process to D-xylulose 5-phosphate
Biological Processdaunorubicin metabolic process
Biological Processdoxorubicin metabolic process
Biological ProcessL-ascorbic acid biosynthetic process

Keywords

  • Ligand
    • #NADP

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    alcohol dehydrogenase (NADP(+))
  • EC number
  • Alternative names
    • S-nitroso-CoA reductase

Gene names

    • Name
      AKR1A1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Telluraves > Australaves > Passeriformes > Passeroidea > Estrildidae > Estrildinae > Taeniopygia

Accessions

  • Primary accession
    H0ZCF8

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain20-295NADP-dependent oxidoreductase

Sequence similarities

Belongs to the aldo/keto reductase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    327
  • Mass (Da)
    37,274
  • Last updated
    2012-02-22 v1
  • Checksum
    9D398CB27C58967F
MPATCDFITLHTGQKMPLVGLGTWKSDRGQVKEAVKHALSVGYRHIDCAAAYSNEAEIGDAFQECVGPNKVIKREDLFVTSKLWNTKHHPEDVEPALRKTLGDMKLDYLDLYLMHWPHAFERGDNLFPKNPDNTMRYDYIDYKDTWKAMEKLVEKGLVKAIGLSNFNSRQIDDVLSVATVKPAVLQVECHPYLAQNELIAHCQKRGLVVTAYSPLGSPDRMWKHPDEPVLLEEPGVKKIAEKYSKSPAQIVLRWQVQRKVVVIPKSVTPARIQQNLQVFDFSLTEEEMSHIGSLNKNWRYIVPMITVDGKLVARDAGHPHYPFNDPY

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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