D7EBK7 · MTRA_METEZ

Function

function

Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.

Catalytic activity

Cofactor

5-hydroxybenzimidazolylcob(I)amide (UniProtKB | Rhea| CHEBI:60494 )

Note: Binds 1 5-hydroxybenzimidazolylcobamide group.

Pathway

One-carbon metabolism; methanogenesis from CO2; methyl-coenzyme M from 5,10-methylene-5,6,7,8-tetrahydromethanopterin: step 2/2.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site855-hydroxybenzimidazolylcob(I)amide (UniProtKB | ChEBI); cofactor

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functioncobalt ion binding
Molecular Functiontetrahydromethanopterin S-methyltransferase activity
Biological Processmethanogenesis, from carbon dioxide
Biological Processmethylation
Biological Processone-carbon metabolic process
Biological Processsodium ion transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Tetrahydromethanopterin S-methyltransferase subunit A
  • EC number
  • Alternative names
    • N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A

Gene names

    • Name
      mtrA
    • Ordered locus names
      Metev_2020

Organism names

Accessions

  • Primary accession
    D7EBK7

Proteomes

Subcellular Location

Cell membrane
; Single-pass membrane protein

Features

Showing features for topological domain, transmembrane.

Type
IDPosition(s)Description
Topological domain1-220Cytoplasmic
Transmembrane221-241Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004030651-241Tetrahydromethanopterin S-methyltransferase subunit A

Interaction

Subunit

The complex is composed of 8 subunits; MtrA, MtrB, MtrC, MtrD, MtrE, MtrF, MtrG and MtrH.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the MtrA family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    241
  • Mass (Da)
    26,048
  • Last updated
    2010-08-10 v1
  • Checksum
    54FBC9BA2336657B
MAEKKEPAEGWPILKGEYEVGDPNNCVAVITCGSHLEGQPMLDAGASIVGPCKTENLGLEKVVSHIISNPNIRYLIVTGAEVKGHITGEAMMMLHKNGVKDNRIVGATGAIPYVENLTEESVERLQQQLEECVDLLGTEDLNTITSKIKELAEKDPGAFDAEPMIIQLEEEEEEEEEGGIKPMSAEIATIQARIRNIEKDMINAGEMNKLHSGVLAGKIEGIMVGLVLSLFVLGLLLFGGM

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP002069
EMBL· GenBank· DDBJ
ADI74849.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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