C6S444 · C6S444_9PLEO
- ProteinATP-dependent DNA helicase PIF1
- Genepif1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids845 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
Cofactor
Features
Showing features for binding site, dna binding.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 380-387 | ATP (UniProtKB | ChEBI) | |||
DNA binding | 782-801 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Cellular Component | nucleus | |
Molecular Function | 5'-3' DNA helicase activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | DNA binding | |
Biological Process | DNA recombination | |
Biological Process | DNA repair | |
Biological Process | mitochondrial genome maintenance | |
Biological Process | telomere maintenance |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-dependent DNA helicase PIF1
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Dothideomycetes > Pleosporomycetidae > Pleosporales > Massarineae > Didymosphaeriaceae > Paraphaeosphaeria
Accessions
- Primary accessionC6S444
Subcellular Location
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 61-131 | Disordered | |||
Compositional bias | 64-113 | Polar residues | |||
Compositional bias | 214-237 | Polar residues | |||
Region | 214-305 | Disordered | |||
Compositional bias | 272-289 | Basic and acidic residues | |||
Domain | 372-535 | AAA+ ATPase | |||
Sequence similarities
Belongs to the helicase family. PIF1 subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length845
- Mass (Da)93,549
- Last updated2009-09-22 v1
- ChecksumE76A7D3ED0E7A72E
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 64-113 | Polar residues | |||
Compositional bias | 214-237 | Polar residues | |||
Compositional bias | 272-289 | Basic and acidic residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AM778550 EMBL· GenBank· DDBJ | CAO85914.1 EMBL· GenBank· DDBJ | Genomic DNA |