C6S444 · C6S444_9PLEO

Function

function

DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, dna binding.

1845100200300400500600700800
Type
IDPosition(s)Description
Binding site380-387ATP (UniProtKB | ChEBI)
DNA binding782-801

GO annotations

AspectTerm
Cellular Componentmitochondrion
Cellular Componentnucleus
Molecular Function5'-3' DNA helicase activity
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionDNA binding
Biological ProcessDNA recombination
Biological ProcessDNA repair
Biological Processmitochondrial genome maintenance
Biological Processtelomere maintenance

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent DNA helicase PIF1
  • EC number
  • Alternative names
    • DNA repair and recombination helicase PIF1

Gene names

    • Name
      pif1
    • Synonyms
      PIF1

Organism names

  • Taxonomic identifier
  • Strain
    • Conio
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Dothideomycetes > Pleosporomycetidae > Pleosporales > Massarineae > Didymosphaeriaceae > Paraphaeosphaeria

Accessions

  • Primary accession
    C6S444

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region61-131Disordered
Compositional bias64-113Polar residues
Compositional bias214-237Polar residues
Region214-305Disordered
Compositional bias272-289Basic and acidic residues
Domain372-535AAA+ ATPase

Sequence similarities

Belongs to the helicase family. PIF1 subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    845
  • Mass (Da)
    93,549
  • Last updated
    2009-09-22 v1
  • Checksum
    E76A7D3ED0E7A72E
MLVALFRLGASLRFTLVKTSPPSRLPYRPTLRQPQLARIGCLASRTLSTAESMFKAAVKNHSAAAPAQTPTPATQQKQQSMAGAFKSSQGTQRPNGTRPLSTLSGNVPKHNSEKRNSGQAHGIKRTSSGLAKALDSQEDAFGYPSLSISDFENDVPSFHNNKTGQSIPLSAVLFDENDFDSDIDLDVEDPATKTTVQYPSLPHTSTVDSAYHSATAQTTPVTKQEPKSSQQIPWSSSPPEHFRAPPKPQQVPAPTKRRTLPWLQNASQVKTEAIEEEQEVARPKKRRSTEATLTATPAPKASKPDYLWNTTQSAIKQQQKTLREAHKKAVAAKVNGGTDEDVKAAAKRKKTTLHRIFLSEEQQNVLNMVVENKKSVFFTGSAGTGKSVLLREIIVGLRRKYVRESDRVAVTASTGLAACNIGGVTLHSFSGIGLGKEPVEDLVKKIRRNAKAKQRWMRTKVLVIDEVSMVDGDLFDKLEQIARTIRNNGRPFGGIQLIITGDFFQLPPVPDYGKVARFAFDAGTWTTSIEHTIGLTHVFRQKDPVFAGMLNEMREGRLTTASIAKFRQLDRPLPASEDNIEATELFPTRQEVERANQARMNQLQGQIYEFESRDGGTVTDKEKRDKLLQSCMVPANIYLKKGAQVMLVKNMDDTLVNGSLGKVTGFMTEQMFAFYRENEDAFLEGADNTTELDALKKLKEKTLGVNTAQLYPVVRFAISDGTTRDLLCKREPWKIELPNGEVQASRDQIPLILAWALSIHKAQGQTLERVRVDLGRVFEKGQAYVALSRATNMAGLQVMRFDASKVMAHEKVRAFYSSLSTAEHVESKAKKGSIEKHLKITKRQA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias64-113Polar residues
Compositional bias214-237Polar residues
Compositional bias272-289Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AM778550
EMBL· GenBank· DDBJ
CAO85914.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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