B8ZMJ8 · FMT_STRPJ
- ProteinMethionyl-tRNA formyltransferase
- Genefmt
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids311 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
Catalytic activity
- L-methionyl-tRNA(fMet) + (6R)-10-formyltetrahydrofolate = N-formyl-L-methionyl-tRNA(fMet) + (6S)-5,6,7,8-tetrahydrofolate + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 110-113 | (6S)-5,6,7,8-tetrahydrofolate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | methionyl-tRNA formyltransferase activity |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMethionyl-tRNA formyltransferase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus
Accessions
- Primary accessionB8ZMJ8
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_1000190044 | 1-311 | Methionyl-tRNA formyltransferase | ||
Structure
Sequence
- Sequence statusComplete
- Length311
- Mass (Da)33,971
- Last updated2009-03-03 v1
- Checksum96A9E4FE6FBF7316
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
FM211187 EMBL· GenBank· DDBJ | CAR69505.1 EMBL· GenBank· DDBJ | Genomic DNA |