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B5E5S3 · NAGB_STRP4

Function

function

Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.

Catalytic activity

Pathway

Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 5/5.

Features

Showing features for active site.

123520406080100120140160180200220
TypeIDPosition(s)Description
Active site62Proton acceptor; for enolization step
Active site128For ring-opening step
Active site130Proton acceptor; for ring-opening step
Active site135For ring-opening step

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionglucosamine-6-phosphate deaminase activity
Molecular Functionidentical protein binding
Biological Processcarbohydrate metabolic process
Biological Processglucosamine catabolic process
Biological ProcessN-acetylglucosamine catabolic process
Biological ProcessN-acetylneuraminate catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glucosamine-6-phosphate deaminase
  • EC number
  • Alternative names
    • GlcN6P deaminase
      (GNPDA
      )
    • Glucosamine-6-phosphate isomerase

Gene names

    • Name
      nagB
    • Ordered locus names
      SPG_1356

Organism names

Accessions

  • Primary accession
    B5E5S3

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001397951-235Glucosamine-6-phosphate deaminase

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    235
  • Mass (Da)
    25,730
  • Last updated
    2008-10-14 v1
  • MD5 Checksum
    EE43F045DCCE4D1858EC473DA895B3CD
MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYKEIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNAEAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARFFAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNHPDVTIIADAEALSLLEK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP001015
EMBL· GenBank· DDBJ
ACF56188.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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