B5E5S3 · NAGB_STRP4
- ProteinGlucosamine-6-phosphate deaminase
- GenenagB
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids235 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
Catalytic activity
- alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4+
Pathway
Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 5/5.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 62 | Proton acceptor; for enolization step | |||
Active site | 128 | For ring-opening step | |||
Active site | 130 | Proton acceptor; for ring-opening step | |||
Active site | 135 | For ring-opening step | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | glucosamine-6-phosphate deaminase activity | |
Molecular Function | identical protein binding | |
Biological Process | carbohydrate metabolic process | |
Biological Process | glucosamine catabolic process | |
Biological Process | N-acetylglucosamine catabolic process | |
Biological Process | N-acetylneuraminate catabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlucosamine-6-phosphate deaminase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus
Accessions
- Primary accessionB5E5S3
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_1000139795 | 1-235 | Glucosamine-6-phosphate deaminase | ||
Structure
Sequence
- Sequence statusComplete
- Length235
- Mass (Da)25,730
- Last updated2008-10-14 v1
- MD5 ChecksumEE43F045DCCE4D1858EC473DA895B3CD
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP001015 EMBL· GenBank· DDBJ | ACF56188.1 EMBL· GenBank· DDBJ | Genomic DNA |