B1L8M5 · LARC_THESQ

  • Protein
    Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein
  • Gene
    larC
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni2+, and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

Catalytic activity

GO annotations

AspectTerm
Molecular Functionlyase activity
Molecular Functionnickel cation binding
Biological Processprotein maturation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein
  • EC number
  • Short names
    P2TMN nickel insertion protein
  • Alternative names
    • Nickel-pincer cofactor biosynthesis protein LarC

Gene names

    • Name
      larC
    • Ordered locus names
      TRQ2_1826

Organism names

Accessions

  • Primary accession
    B1L8M5

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10001366971-402Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein

Structure

Family & Domains

Sequence similarities

Belongs to the LarC family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    402
  • Mass (Da)
    44,859
  • Last updated
    2008-04-29 v1
  • MD5 Checksum
    831490CD3B1BF0B8534102948CED068C
MRILYLDPFSGISGDMFLGLLVDLGVDPEKIKSRLEKLNVEFEFVVKKENKKGVTATKVDVVFPGKEHHEDHIVSDHDHHHHHGRHLSEIVEVLSRLEDPLKEKAIRMFETLAEAESKIHGLSKEKVHFHEVGAMDAVIEIAGAVAGLELLGVEKVFCGTVNTGSGFVMTEHGRYPVPAPATAELLKGIPIYVDQKVRTELVTPTGAVILKSLVDEFRTPILRVEKVGYGAGTMDLEIPNVLRGYLGYIEPSERTGDVLIETNVDDMSPQLFGHLMERLFEAGAKDVFFTPIYMKKNRPAVKVSVLCHESKKDEILKLLFKESTSIGARVFYPEKVEATRTVKTVKTEYGEIPVKIASFDSEIVNISPEYEACKKIAQEKGIPLKEVYRAVCKSVSEVRDDV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000969
EMBL· GenBank· DDBJ
ACB10154.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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