B1L8M5 · LARC_THESQ
- ProteinPyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein
- GenelarC
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids402 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni2+, and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.
Catalytic activity
- Ni(II)-pyridinium-3,5-bisthiocarboxylate mononucleotide = pyridinium-3,5-bisthiocarboxylate mononucleotide + Ni2+
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | lyase activity | |
Molecular Function | nickel cation binding | |
Biological Process | protein maturation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein
- EC number
- Short namesP2TMN nickel insertion protein
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Thermotogota > Thermotogae > Thermotogales > Thermotogaceae > Thermotoga
Accessions
- Primary accessionB1L8M5
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_1000136697 | 1-402 | Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein | ||
Structure
Sequence
- Sequence statusComplete
- Length402
- Mass (Da)44,859
- Last updated2008-04-29 v1
- MD5 Checksum831490CD3B1BF0B8534102948CED068C
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000969 EMBL· GenBank· DDBJ | ACB10154.1 EMBL· GenBank· DDBJ | Genomic DNA |