B0BNW7 · RLMM_ACTPJ
- ProteinRibosomal RNA large subunit methyltransferase M
- GenerlmM
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids361 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
Catalytic activity
- cytidine2498 in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine2498 in 23S rRNA + S-adenosyl-L-homocysteine + H+
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 190 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 223-226 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 242 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 262 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 280 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Active site | 309 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | S-adenosylmethionine-dependent methyltransferase activity | |
Biological Process | methylation | |
Biological Process | rRNA processing |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRibosomal RNA large subunit methyltransferase M
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pasteurellales > Pasteurellaceae > Actinobacillus
Accessions
- Primary accessionB0BNW7
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_1000201507 | 1-361 | Ribosomal RNA large subunit methyltransferase M | ||
Interaction
Subunit
Monomer.
Structure
Family & Domains
Sequence similarities
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length361
- Mass (Da)41,493
- Last updated2008-02-26 v1
- ChecksumBF9646107F5F29CF
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000687 EMBL· GenBank· DDBJ | ABY69252.1 EMBL· GenBank· DDBJ | Genomic DNA |