A6XHF7 · MCPB_TRIRU

Function

function

Extracellular metalloprotease that contributes to pathogenicity.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Features

Showing features for binding site, active site.

153850100150200250300350400450500
Type
IDPosition(s)Description
Binding site136Zn2+ (UniProtKB | ChEBI); catalytic
Binding site139Zn2+ (UniProtKB | ChEBI); catalytic
Binding site224Zn2+ (UniProtKB | ChEBI); catalytic
Active site322Proton donor/acceptor

GO annotations

AspectTerm
Cellular Componentextracellular space
Molecular Functionmetallocarboxypeptidase activity
Molecular Functionzinc ion binding
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Carboxypeptidase 2
  • EC number
  • Alternative names
    • Carboxypeptidase M14B
    • Carboxypeptidase MCPB

Gene names

    • Name
      MCPB
    • Synonyms
      CARB2

Organism names

Accessions

  • Primary accession
    A6XHF7

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, glycosylation.

Type
IDPosition(s)Description
Signal1-21
ChainPRO_000038411122-538Carboxypeptidase 2
Glycosylation46N-linked (GlcNAc...) asparagine
Glycosylation393N-linked (GlcNAc...) asparagine
Glycosylation459N-linked (GlcNAc...) asparagine

Keywords

PTM databases

Family & Domains

Features

Showing features for compositional bias, region, domain.

Type
IDPosition(s)Description
Compositional bias53-73Polar residues
Region53-76Disordered
Domain71-351Peptidase M14

Sequence similarities

Belongs to the peptidase M14 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    538
  • Mass (Da)
    59,861
  • Last updated
    2007-08-21 v1
  • Checksum
    C5309457D7706DA4
MVAYRFLTLISLGLGSHCVSALQYGYNQLSTHKDPAVVAGAFPAINGTHLRSPAFTSPGTVSRGFSDGTSGPTRDETMEGFMRRLARSNSWMAYHEAGFKSEEGRKFPYMYLSASSSSVENPSSRKLRVWLQGGVHGNEPAGDQSMLVLLGDLAANQKWAAKLLEKMDILVLPRYNPDGVFYFQRYLATNFDPNRDHLKLARQQTRDIKELFAKFSPHIATDMHEFTAGRAFGPKKDFIYAADALFSAAKNLNIDEGIRQLSEKLFAKRMGKDIEAAGLRWDPYITLGESSSSKLLLREAGTDAKIGRNAMGLSQCVVFLCETRGIGIADQHFERRTLSGLVMAKSVLQTAVDNFDEVYNTIERGIRRFTNSRNDIVLTDKSPIIERTFGMLNTTDASLFDYPIDFATTTPAEPVLTRSRPRAYLIPPSWPDIVKRLEVFGVKADKLPYSYVGPVEALNVTSVTFDKEFYEGVVTTTVETKLVERSIRLPPGSYLVKTNQKNAALAFVALEPENIDSFASFGIIPVNTGDQYPIFRLK

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias53-73Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
EU024296
EMBL· GenBank· DDBJ
ABW79918.1
EMBL· GenBank· DDBJ
Genomic DNA
DQ786567
EMBL· GenBank· DDBJ
ABH03555.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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