A4FQD4 · MSHD_SACEN
- ProteinMycothiol acetyltransferase
- GenemshD
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids303 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
Catalytic activity
- 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = mycothiol + CoA + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 18 | 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI) | |||
Binding site | 77-79 | acetyl-CoA 1 (UniProtKB | ChEBI) | |||
Binding site | 189 | 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI) | |||
Binding site | 229 | 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI) | |||
Binding site | 237 | 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI) | |||
Binding site | 241-243 | acetyl-CoA 2 (UniProtKB | ChEBI) | |||
Binding site | 248-254 | acetyl-CoA 2 (UniProtKB | ChEBI) | |||
Binding site | 275 | 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI) | |||
Binding site | 280-285 | acetyl-CoA 2 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | mycothiol synthase activity | |
Molecular Function | peptide-alanine-alpha-N-acetyltransferase activity | |
Biological Process | mycothiol biosynthetic process | |
Biological Process | N-terminal peptidyl-alanine acetylation |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMycothiol acetyltransferase
- EC number
- Short namesMSH acetyltransferase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Pseudonocardiales > Pseudonocardiaceae > Saccharopolyspora
Accessions
- Primary accessionA4FQD4
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000400295 | 1-303 | Mycothiol acetyltransferase | ||
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 1-150 | N-acetyltransferase 1 | |||
Domain | 162-303 | N-acetyltransferase 2 | |||
Sequence similarities
Belongs to the acetyltransferase family. MshD subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length303
- Mass (Da)33,638
- Last updated2007-04-17 v1
- Checksum805C202662AC447E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AM420293 EMBL· GenBank· DDBJ | CAM06259.1 EMBL· GenBank· DDBJ | Genomic DNA |