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A3F5L3 · DES2_SORBI

Function

function

Delta12 fatty acid desaturase converting palmitoleic acid (16:19) to hexadecadienoic acid (16:2(9,12)). No detectable Delta12linoleate desaturase activity. Involved in the biosynthesis of the aliphatic side chain of sorgoleone, a phytotoxic secondary metabolite playing a direct role in allelopathic interactions.

Pathway

Lipid metabolism; polyunsaturated fatty acid biosynthesis.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Molecular Functionoxidoreductase activity
Molecular Functionoxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
Biological Processunsaturated fatty acid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Fatty acid desaturase DES2
  • EC number
  • Short names
    SbDES2

Gene names

    • Name
      DES2
    • ORF names
      SORBIDRAFT_04g029900
    • Ordered locus names
      Sb04g029900

Organism names

  • Taxonomic identifier
  • Strain
    • cv. BTx623
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > PACMAD clade > Panicoideae > Andropogonodae > Andropogoneae > Sorghinae > Sorghum

Accessions

  • Primary accession
    A3F5L3

Proteomes

Genome annotation databases

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane65-85Helical
Transmembrane89-109Helical
Transmembrane122-142Helical
Transmembrane185-205Helical
Transmembrane231-251Helical
Transmembrane254-274Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004344021-385Fatty acid desaturase DES2

Expression

Tissue specificity

Highly expressed in root hair cells. Barely detected in panicle, shoot apex, stems and leaves.

Induction

Up-regulated upon auxin treatment (PubMed:22087851).
Up-regulated by jasmonate and methyl jasmonate (PubMed:23702703).

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, motif.

Type
IDPosition(s)Description
Region1-33Disordered
Motif110-114Histidine box-1
Motif146-150Histidine box-2
Motif321-325Histidine box-3

Domain

The histidine box domains may contain the active site and/or be involved in metal ion binding.

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    385
  • Mass (Da)
    44,209
  • Last updated
    2007-03-20 v1
  • MD5 Checksum
    238D7347CCFD72463CA2E24EFF6FA8B8
MGAGGKMTEQEREKQEQQLARGASTMQRSPVEKPPFTVGQIKKAIPPHCFQRSVLKSFSYVVRDLVIAAALLYFALAIIPALPSPLHYAAWPLYWIAQGCVCFAMWVIAHECGHHAFSDYQLLDDIVGLVLHSSLMVPYFSWKYSHRRHHSNTGSLERDEVFVPKTKGALAWYAPYVYNNPVGRLVHIVVQLTLGWPLYLATNVSGRPYPRFACHYDPYGPIYNDRERAQIFVSDAGVMAVSFGLYKLAATLGFWWVVRVYAVPLLIVNVWLVLVTYLHHTHPALPHYDSREWDWLRGALSTVDRDYGVFNRFFHNITDTHVVHHLFSTLPHFHATEATKAIKPILGEYYQFDPTPIAKATWREARECIFVEPEEGRGVFWYNKF

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
EF206347
EMBL· GenBank· DDBJ
ABN49520.1
EMBL· GenBank· DDBJ
mRNA
CM000763
EMBL· GenBank· DDBJ
EES05625.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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