A1SPL0 · MSHD_NOCSJ
- ProteinMycothiol acetyltransferase
- GenemshD
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids295 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
Catalytic activity
- 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = mycothiol + CoA + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 30 | 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI) | |||
Binding site | 62-64 | acetyl-CoA 1 (UniProtKB | ChEBI) | |||
Binding site | 165 | 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI) | |||
Binding site | 209 | 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI) | |||
Binding site | 227 | 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI) | |||
Binding site | 231-233 | acetyl-CoA 2 (UniProtKB | ChEBI) | |||
Binding site | 238-244 | acetyl-CoA 2 (UniProtKB | ChEBI) | |||
Binding site | 265 | 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | mycothiol synthase activity | |
Molecular Function | peptide-alanine-alpha-N-acetyltransferase activity | |
Biological Process | mycothiol biosynthetic process | |
Biological Process | N-terminal peptidyl-alanine acetylation |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMycothiol acetyltransferase
- EC number
- Short namesMSH acetyltransferase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Propionibacteriales > Nocardioidaceae > Nocardioides
Accessions
- Primary accessionA1SPL0
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000400286 | 1-295 | Mycothiol acetyltransferase | ||
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 137-295 | N-acetyltransferase | |||
Sequence similarities
Belongs to the acetyltransferase family. MshD subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length295
- Mass (Da)30,832
- Last updated2007-02-06 v1
- Checksum66A164AED8AB7224
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000509 EMBL· GenBank· DDBJ | ABL83745.1 EMBL· GenBank· DDBJ | Genomic DNA |