A0AA39U6H9 · A0AA39U6H9_9PEZI
- ProteinGMP synthase [glutamine-hydrolyzing]
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids542 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate.
Catalytic activity
- XMP + L-glutamine + ATP + H2O = GMP + L-glutamate + AMP + diphosphate + 2 H+
Pathway
Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 92 | Nucleophile | |||
Active site | 184 | ||||
Active site | 186 | ||||
Binding site | 239-245 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | GMP synthase activity | |
Biological Process | glutamine metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGMP synthase [glutamine-hydrolyzing]
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Sordariomycetidae > Sordariales > Lasiosphaeriaceae > Bombardia
Accessions
- Primary accessionA0AA39U6H9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length542
- Mass (Da)59,732
- Last updated2024-01-24 v1
- MD5 Checksum6F8143D432C109B5B1DCD9D62B8AB8A0
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAULSR010000008 EMBL· GenBank· DDBJ | KAK0612875.1 EMBL· GenBank· DDBJ | Genomic DNA |