A0A9P0AH13 · A0A9P0AH13_BEMTA

Function

Catalytic activity

  • heme b(in) + ATP + H2O = heme b(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
    EC:7.6.2.5 (UniProtKB | ENZYME | Rhea)
  • pheophorbide a(in) + ATP + H2O = pheophorbide a(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • protoporphyrin IX(in) + ATP + H2O = protoporphyrin IX(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • uroporphyrin I(in) + ATP + H2O = uroporphyrin I(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • uroporphyrin III(in) + ATP + H2O = uroporphyrin III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrin I(in) + ATP + H2O = coproporphyrin I(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrin III(in) + ATP + H2O = coproporphyrin III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrinogen III(in) + ATP + H2O = coproporphyrinogen III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.

GO annotations

AspectTerm
Cellular Componentearly endosome membrane
Cellular Componentextracellular region
Cellular ComponentGolgi membrane
Cellular Componentlysosomal membrane
Cellular Componentmelanosome membrane
Cellular Componentmitochondrial outer membrane
Cellular Componentmultivesicular body membrane
Molecular FunctionABC-type heme transporter activity
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular Functionheme binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-binding cassette sub-family B member 6
  • EC number
  • Alternative names
    • ABC-type heme transporter ABCB6

Gene names

    • ORF names
      BEMITA_LOCUS10268

Organism names

Accessions

  • Primary accession
    A0A9P0AH13

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Early endosome membrane
Endoplasmic reticulum membrane
; Multi-pass membrane protein
Endosome membrane
; Multi-pass membrane protein
Golgi apparatus membrane
; Multi-pass membrane protein
Late endosome membrane
Lysosome membrane
Melanosome membrane
Mitochondrion outer membrane
; Multi-pass membrane protein
Secreted, extracellular exosome

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane28-48Helical
Transmembrane69-89Helical
Transmembrane95-118Helical
Transmembrane130-153Helical
Transmembrane173-191Helical
Transmembrane246-264Helical
Transmembrane369-392Helical
Transmembrane398-418Helical
Transmembrane480-506Helical
Transmembrane518-541Helical

Keywords

PTM/Processing

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain, compositional bias, region.

Type
IDPosition(s)Description
Domain253-543ABC transmembrane type-1
Domain577-811ABC transporter
Compositional bias812-830Polar residues
Region812-837Disordered

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    837
  • Mass (Da)
    94,419
  • Last updated
    2023-09-13 v1
  • Checksum
    53AB9126C173BE65
MMKFCPPNVTFSEIWVNHGVSQCFMETVYAGLLVGFLFIFGTIQLFYYRKYSTPVMVSFPASKLFRVQIAITVLLAVVTISRFVVEAIIINHGIIYGYMIFSTVGLVSTIIFSLILIFKERHYLLPSIPSCGHGLVLLIFWSILFIGENLTFINLGRSDWWFQIKTKEDKIEMALFVTRYLLCSVIFILGLRAPGIITSREYFNLTNSAAENMESGPNVESNQSTWHSGWKKIKTLMPFLWPRKSIFLQLRVLICFTLLIGGRLTNFYVPKMGQEIVDSMTGTTMVFPWELVVIYAGLKLLQGGGTGGTGLLNNVRSVLWVSVQQYNTRELEVSLFSHLHGLSLGWHLSRKTGEVLRIMDRGANSINNILSYILFNLVPTLVDIVVAIVYFIVAFNVWYGLIVFTTMFLYLVATIGITEWRTKFQRSMNLKDNAVKARTADSLLNFETVKYYCAEDFEVQEYRHSIFDYQKEEWKTQMSLALLNLFQNTVICIGLLIGTLLCVHQVTIERTLTIGDYFLFTTYIFQLYVPLNWFGTFYRAIQGSFIDMENMFELMDEAPDVLDAPDAPPLVISKGQIDFRNVSFSYQPEKMILKNINFTVPGGKTVALVGPSGSGKSTIVRLLFRFYDANSGAVLVDGQNIKTVLQKSLREVIGVVPQDTVLFNNSIKFNIAYGRISATDSEIVAAAQNADIHEKILTFPKGYDTVVGERGLKLSGGEKQRIAIARTILKAPSIILLDEATSSLDTQTERNIQTALARVSANKTTLIVAHRLSTVINADEILVLKEGEIVERGRHEELLNLNGLYASMWNEQQKSQKQSDAENSGTSLDFSGDLEKK

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias812-830Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
OU963867
EMBL· GenBank· DDBJ
CAH0391670.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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