A0A9N8RRP6 · A0A9N8RRP6_9BURK
- ProteinProbable peptidoglycan glycosyltransferase FtsW
- GeneftsW
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids422 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Peptidoglycan polymerase that is essential for cell division.
Catalytic activity
- [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H+
[GlcNAc-(1→4)-Mur2Ac(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate RHEA-COMP:9602 + CHEBI:60033 = [GlcNAc-(1→4)-Mur2Ac(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate RHEA-COMP:9603 + CHEBI:58405 + CHEBI:15378
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cell division site | |
Cellular Component | plasma membrane | |
Molecular Function | lipid-linked peptidoglycan transporter activity | |
Molecular Function | peptidoglycan glycosyltransferase activity | |
Biological Process | cell wall organization | |
Biological Process | FtsZ-dependent cytokinesis | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | regulation of cell shape |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProbable peptidoglycan glycosyltransferase FtsW
- EC number
- Short namesPGT
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Paraburkholderia
Accessions
- Primary accessionA0A9N8RRP6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Cell membrane ; Multi-pass membrane protein
Note: Localizes to the division septum.
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 53-75 | Helical | |||
Transmembrane | 87-110 | Helical | |||
Transmembrane | 122-139 | Helical | |||
Transmembrane | 159-175 | Helical | |||
Transmembrane | 187-204 | Helical | |||
Transmembrane | 210-227 | Helical | |||
Transmembrane | 234-252 | Helical | |||
Transmembrane | 310-335 | Helical | |||
Transmembrane | 347-366 | Helical | |||
Transmembrane | 386-409 | Helical | |||
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-34 | Disordered | |||
Compositional bias | 18-34 | Polar residues | |||
Sequence similarities
Belongs to the SEDS family. FtsW subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length422
- Mass (Da)45,896
- Last updated2023-09-13 v1
- MD5 Checksum1DD0CEA32634DB3DCBD0E136AC6E8E97
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 18-34 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CAJQZC010000001 EMBL· GenBank· DDBJ | CAG4885551.1 EMBL· GenBank· DDBJ | Genomic DNA |