A0A8M9PBN5 · A0A8M9PBN5_DANRE

Function

function

Required for anchoring microtubules to the centrosomes. Required for ciliation.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcell projection
Cellular Componentcentrosome
Molecular Functioncalcium ion binding
Biological Processcell projection organization
Biological Processmicrotubule anchoring

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Centrosomal protein 43
  • Alternative names
    • FGFR1 oncogene partner

Gene names

    • Name
      cep43
    • Synonyms
      ccr6a
      , fgfr1op
      , zgc:86782

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio

Accessions

  • Primary accession
    A0A8M9PBN5

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Keywords

Interaction

Subunit

Homodimer. Part of a ternary complex that contains CEP350, CEP43 and MAPRE1. Interacts directly with CEP350 and MAPRE1. Interacts with CEP19. Interacts (via N-terminus) with CEP350 (via C-terminus).

Family & Domains

Features

Showing features for domain, compositional bias, region.

Type
IDPosition(s)Description
Domain156-191EF-hand
Compositional bias271-293Basic and acidic residues
Region271-515Disordered
Compositional bias363-391Basic and acidic residues
Compositional bias396-415Polar residues
Compositional bias427-446Polar residues
Compositional bias457-476Basic and acidic residues

Sequence similarities

Belongs to the CEP43 family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    515
  • Mass (Da)
    56,653
  • Last updated
    2022-08-03 v1
  • Checksum
    7D5222A2B3831E69
MSATEEDTELRDLLIQNLENSGVLNKIKAELRAAVFLALEEQDKVENKTPLVNENLKKSLNTKDGRLVAGLITDFLQVFNLDFTLAVFQPEISTLNGLDSREVLSKELGISESEVNKNSPLLLELVKRGRHREKTSIFTEGDRVADRTFPKELLPRQIAEARKKFDSHDKNRSGEINRDAVIGIFADLFPQFSRNMLDCYVTEELRAKGKDTSSTIDFQDFLGMYKCFFIQCRSVVTSDNSDALYSSSKTTEDKIILSSASKIPRFKGFVKHSSAQEEKADPKAGDRRPGELLGSPKIRGSVQVSEGSEEESGLGDGKNLPTPLKRALEFGLEDEEEEGDSFFDDPLPKPQKTYGCLSAIGSDKEGDGEDMLSDCESRPTPDSERRREGLGGSLGKAFTSGTQLKSAGGSISAESSKKDHSSDKNGTSLSIDKGGKDFSTPNEKTGSPLLDDDLDYDDDFNSHRSENSKSEVSIDEEIEEVSIEGPDISDKLDETTQDVSVSQTSLGADYMEDVA

Computationally mapped potential isoform sequences

There are 8 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8M9PSK8A0A8M9PSK8_DANREcep43563
A0A0R4IW74A0A0R4IW74_DANREcep43487
A0A8M9PP81A0A8M9PP81_DANREcep43557
A0A8M9P2I3A0A8M9P2I3_DANREcep43542
A0A8M2B7I9A0A8M2B7I9_DANREcep43508
A0A8M2B7J0A0A8M2B7J0_DANREcep43538
Q6IQF6Q6IQF6_DANREcep43511
A0A8M6YUS2A0A8M6YUS2_DANREcep43485

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias271-293Basic and acidic residues
Compositional bias363-391Basic and acidic residues
Compositional bias396-415Polar residues
Compositional bias427-446Polar residues
Compositional bias457-476Basic and acidic residues

Keywords

Sequence databases

Similar Proteins

Disclaimer

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