A0A8K0TV84 · A0A8K0TV84_9AGAM
- Proteinglycine hydroxymethyltransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids486 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Interconversion of serine and glycine.
Catalytic activity
- (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine
Cofactor
Pathway
One-carbon metabolism; tetrahydrofolate interconversion.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | cobalt ion binding | |
Molecular Function | glycine hydroxymethyltransferase activity | |
Molecular Function | pyridoxal phosphate binding | |
Molecular Function | serine binding | |
Molecular Function | zinc ion binding | |
Biological Process | folic acid metabolic process | |
Biological Process | glycine biosynthetic process from serine | |
Biological Process | L-serine catabolic process | |
Biological Process | tetrahydrofolate interconversion |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameglycine hydroxymethyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Boletales > Sclerodermatineae > Boletinellaceae > Phlebopus
Accessions
- Primary accessionA0A8K0TV84
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Modified residue | 254 | N6-(pyridoxal phosphate)lysine | |||
Structure
Sequence
- Sequence statusComplete
- Length486
- Mass (Da)53,248
- Last updated2022-08-03 v1
- ChecksumD840F51C908CD9DA
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAEVFL010000012 EMBL· GenBank· DDBJ | KAH7882387.1 EMBL· GenBank· DDBJ | Genomic DNA |