A0A8C9WZ66 · A0A8C9WZ66_SANLU

Function

Catalytic activity

  • 1,2-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H+ = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O
    This reaction proceeds in the forward direction.
  • 1,2-di-(9Z-octadecenoyl)-sn-glycerol + (9Z)-octadecenoyl-CoA = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 1,3-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 1-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 1-O-(9Z-octadecenyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-O-(9Z-octadecenyl)-2,3-di-(9Z-octadecenoyl)glycerol + CoA
    This reaction proceeds in the forward direction.
  • 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-3-(9Z)-octadecenoyl-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 2,3-di-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoyl-CoA = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 1,2-di-(9Z-octadecenoyl)-sn-glycerol + hexadecanoyl-CoA = 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
  • 13-cis-retinol + hexadecanoyl-CoA = 13-cis-retinyl hexadecanoate + CoA
    This reaction proceeds in the forward direction.
  • 2-(9Z-octadecenoyl)-glycerol + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
  • an acyl-CoA + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + CoA
    This reaction proceeds in the forward direction.
    EC:2.3.1.20 (UniProtKB | ENZYME | Rhea)
  • all-trans-retinol + an acyl-CoA = an all-trans-retinyl ester + CoA
    This reaction proceeds in the forward direction.
    EC:2.3.1.76 (UniProtKB | ENZYME | Rhea)
  • all-trans-retinol + hexadecanoyl-CoA = all-trans-retinyl hexadecanoate + CoA
    This reaction proceeds in the forward direction.
  • hexadecan-1-ol + hexadecanoyl-CoA = hexadecanyl hexadecanoate + CoA
    This reaction proceeds in the forward direction.
  • hexadecane-1,2-diol + 2 hexadecanoyl-CoA = 1,2-O,O-dihexadecanoyl-1,2-hexadecanediol + 2 CoA
    This reaction proceeds in the forward direction.
  • hexadecane-1,2-diol + hexadecanoyl-CoA = 2-hydroxyhexadecyl hexadecanoate + CoA
    This reaction proceeds in the forward direction.

Pathway

Lipid metabolism; glycerolipid metabolism.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site460

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functiondiacylglycerol O-acyltransferase activity
Biological Processtriglyceride biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    O-acyltransferase

Gene names

    • Name
      dgat1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Eupercaria > Perciformes > Percoidei > Percidae > Luciopercinae > Sander

Accessions

  • Primary accession
    A0A8C9WZ66

Proteomes

Subcellular Location

Endoplasmic reticulum membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane124-145Helical
Transmembrane165-186Helical
Transmembrane198-222Helical
Transmembrane228-245Helical
Transmembrane327-346Helical
Transmembrane377-398Helical
Transmembrane446-465Helical
Transmembrane471-489Helical
Transmembrane501-519Helical

Keywords

Interaction

Subunit

Homodimer or homotetramer; both forms have similar enzymatic activities.

Family & Domains

Features

Showing features for compositional bias, region.

Type
IDPosition(s)Description
Compositional bias1-19Basic and acidic residues
Region1-85Disordered
Compositional bias61-85Polar residues

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    530
  • Mass (Da)
    61,152
  • Last updated
    2022-01-19 v1
  • Checksum
    452BB8F4E282B9AF
MTEAAEMSDRAEMRGPVSRRRRTTISGGGGSGAVKQANGSKWHDAGEKLPLYPAKAKTDEVPRQASNNGKVDREMGMSGQQQQLAKRTRKQRSLVEDINEKLSCHVLQESLLSSASGYSNYRGILNWCVVMLVLSNARLFLENIIKYGILVDPIQVVSLFLKDPYSWPAACLIIVSNVFILAALYTERRLAVGTITQMTGLIFHIFNLTSMLIFPSATVLIVTSMTPVGGVLSLGIYTVLFLKLYSYQDTNRWCREIRQAKAKRLTRSYSCPSVAQSNGSAGHTHVSYPGNLTHRDMYYFVFAPTLCYQLNFPRSPRIRIRFLMRRLFEMLFFMQLLVGLIQQWMVPTIQNSMKPFQEMDFSRMVERLLKLAVPNHLIWLIFFYWFFHSSMNFVAELLQFGDREFYKDWWNSETVTYFWANWNIPVHKWCLRHFYKPMLRKGVNKFLAQTAVFLMSAFFHEYLVSVPLKMFRLWAFMGMMAQVPLAWFVGRFLNGNYGNAAVWMSLIIGQPVAVLMYVHDYYVIHYGSTT

Computationally mapped potential isoform sequences

There are 5 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8D0CP91A0A8D0CP91_SANLUdgat1516
A0A8C9WWV8A0A8C9WWV8_SANLUdgat1418
A0A8C9WWP5A0A8C9WWP5_SANLUdgat1407
A0A8C9WTN1A0A8C9WTN1_SANLUdgat1426
A0A8C9WSJ4A0A8C9WSJ4_SANLUdgat1496

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-19Basic and acidic residues
Compositional bias61-85Polar residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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