A0A829GPX3 · A0A829GPX3_LACPA
- ProteinPhosphopantetheine adenylyltransferase
- GenecoaD
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids167 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
Catalytic activity
- (R)-4'-phosphopantetheine + ATP + H+ = 3'-dephospho-CoA + diphosphate
Cofactor
Pathway
Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.
Features
Showing features for binding site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 11 | substrate | |||
Binding site | 11-12 | ATP (UniProtKB | ChEBI) | |||
Binding site | 19 | ATP (UniProtKB | ChEBI) | |||
Site | 19 | Transition state stabilizer | |||
Binding site | 43 | substrate | |||
Binding site | 76 | substrate | |||
Binding site | 90 | substrate | |||
Binding site | 91-93 | ATP (UniProtKB | ChEBI) | |||
Binding site | 101 | ATP (UniProtKB | ChEBI) | |||
Binding site | 126-132 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | pantetheine-phosphate adenylyltransferase activity | |
Biological Process | coenzyme A biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphopantetheine adenylyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Lactobacillaceae > Lacticaseibacillus
Accessions
- Primary accessionA0A829GPX3
Proteomes
Subcellular Location
Interaction
Subunit
Homohexamer.
Structure
Sequence
- Sequence statusComplete
- Length167
- Mass (Da)18,129
- Last updated2021-09-29 v1
- MD5 Checksum363EFE7C2241653750B2292BD01448B2
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
ANKB01000128 EMBL· GenBank· DDBJ | EPC62290.1 EMBL· GenBank· DDBJ | Genomic DNA |