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A0A7V9FRY4 · A0A7V9FRY4_9PSEU

Function

function

May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

NAD+ (UniProtKB | Rhea| CHEBI:57540 )

Note: Binds 1 NAD+ per subunit.

Pathway

Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site67substrate
Binding site151substrate
Binding site213substrate
Binding site214-216NAD+ (UniProtKB | ChEBI)
Binding site243substrate
Binding site247substrate
Binding site248NAD+ (UniProtKB | ChEBI)
Binding site277-282NAD+ (UniProtKB | ChEBI)
Binding site279-284NAD+ (UniProtKB | ChEBI)
Binding site300NAD+ (UniProtKB | ChEBI)
Binding site335NAD+ (UniProtKB | ChEBI)
Binding site356-358NAD+ (UniProtKB | ChEBI)
Binding site404NAD+ (UniProtKB | ChEBI)
Binding site411NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionadenosylhomocysteinase activity
Biological ProcessL-homocysteine biosynthetic process
Biological Processone-carbon metabolic process
Biological ProcessS-adenosylmethionine cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosylhomocysteinase
  • EC number
  • Alternative names
    • S-adenosyl-L-homocysteine hydrolase
      (AdoHcyase
      )

Gene names

    • Name
      ahcY
    • ORF names
      H0V41_03430

Organism names

Accessions

  • Primary accession
    A0A7V9FRY4

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain248-410S-adenosyl-L-homocysteine hydrolase NAD binding

Sequence similarities

Belongs to the adenosylhomocysteinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    490
  • Mass (Da)
    53,539
  • Last updated
    2021-06-02 v1
  • MD5 Checksum
    47FE54FE7B44A63DE478EB7D3FC63234
MAPAAEKKLQTRAGIDFAVADLGLAEFGRNEIRLAQHEMPGLMALRREYADVFPLRGARISGSLHMTVQTAVLIETLVSLGAEVRWASCNIFSTQDHSAAAVVVGPYGTAEEPQGVPCFAWKGETLEEYWWCTERMLTWPDGAGPNMILDDGGDATMVVHKATTFEKAGVVPAPDENDSDEWKVFLNVLRASLAATPGKWTAIGEGIRGVTEETTTGVHRLYQLAAAGQLLFPAINVNDSVTKSKFDNKYGCRHSLVDGINRAVDVLIAGKLCVVCGYGDVGKGCSESLRGQGARVVVAEVDPICALQAMMDGFTVDTLDNVVGRADIIITATGNKDIVTVDHMSRMKHQAILGNIGHFDNEIDMAGLERRSGARRLVIKPQVDEWTFKDGHSIILLSEGRLLNLGNATGHPSFVMSNSFSNQVIAQVELFTKYQEYDREVYTLPKVLDEKVARIHVEALGGELTKLTKEQAEYIDVDVEGPYKPAHYRY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACCZB010000086
EMBL· GenBank· DDBJ
MBA2471324.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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