A0A7V9FRY4 · A0A7V9FRY4_9PSEU
- ProteinAdenosylhomocysteinase
- GeneahcY
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids490 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
Catalytic activity
- S-adenosyl-L-homocysteine + H2O = L-homocysteine + adenosine
Cofactor
Note: Binds 1 NAD+ per subunit.
Pathway
Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 67 | substrate | |||
Binding site | 151 | substrate | |||
Binding site | 213 | substrate | |||
Binding site | 214-216 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 243 | substrate | |||
Binding site | 247 | substrate | |||
Binding site | 248 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 277-282 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 279-284 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 300 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 335 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 356-358 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 404 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 411 | NAD+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | adenosylhomocysteinase activity | |
Biological Process | L-homocysteine biosynthetic process | |
Biological Process | one-carbon metabolic process | |
Biological Process | S-adenosylmethionine cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAdenosylhomocysteinase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Pseudonocardiales
Accessions
- Primary accessionA0A7V9FRY4
Proteomes
Subcellular Location
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length490
- Mass (Da)53,539
- Last updated2021-06-02 v1
- MD5 Checksum47FE54FE7B44A63DE478EB7D3FC63234
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JACCZB010000086 EMBL· GenBank· DDBJ | MBA2471324.1 EMBL· GenBank· DDBJ | Genomic DNA |