A0A7K9M673 · A0A7K9M673_OCETE
- ProteinPeroxisomal acyl-coenzyme A oxidase 1
- GeneAcox1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids625 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + O2 = (2E,5Z,8Z,11Z,14Z,17Z)-icosahexaenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + O2 = (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- octadecanoyl-CoA + O2 = (2E)-octadecenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- octanoyl-CoA + O2 = (2E)-octenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- tetracosanoyl-CoA + O2 = (2E)-tetracosenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- tetradecanoyl-CoA + O2 = (2E)-tetradecenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- decanoyl-CoA + O2 = (2E)-decenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- dodecanoyl-CoA + O2 = (2E)-dodecenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- glutaryl-CoA + O2 = (2E)-glutaconyl-CoA + H2O2This reaction proceeds in the forward direction.
- hexadecanedioyl-CoA + O2 = (2E)-hexadecenedioyl-CoA + H2O2This reaction proceeds in the forward direction.
- hexadecanoyl-CoA + O2 = (2E)-hexadecenoyl-CoA + H2O2This reaction proceeds in the forward direction.
- hexanoyl-CoA + O2 = (2E)-hexenoyl-CoA + H2O2This reaction proceeds in the forward direction.
Cofactor
Pathway
Lipid metabolism; peroxisomal fatty acid beta-oxidation.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 103 | FAD (UniProtKB | ChEBI) | |||
Binding site | 142 | FAD (UniProtKB | ChEBI) | |||
Active site | 385 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | peroxisome | |
Molecular Function | FAD binding | |
Molecular Function | fatty acid binding | |
Molecular Function | palmitoyl-CoA oxidase activity | |
Biological Process | fatty acid beta-oxidation using acyl-CoA oxidase | |
Biological Process | lipid homeostasis | |
Biological Process | very long-chain fatty acid metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePeroxisomal acyl-coenzyme A oxidase 1
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Aequornithes > Procellariiformes > Hydrobatidae > Oceanodroma
Accessions
- Primary accessionA0A7K9M673
Proteomes
Subcellular Location
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 2-97 | Acyl-coenzyme A oxidase N-terminal | |||
Domain | 100-208 | Acyl-CoA oxidase/dehydrogenase middle | |||
Domain | 239-400 | Acyl-CoA oxidase C-alpha1 | |||
Domain | 444-621 | Acyl-CoA oxidase C-terminal | |||
Sequence similarities
Belongs to the acyl-CoA oxidase family.
Family and domain databases
Sequence
- Sequence statusFragment
- Length625
- Mass (Da)70,357
- Last updated2021-04-07 v1
- MD5 Checksum0EFB6AD9A3BF368D6C746BCF081990FD
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Non-terminal residue | 1 | ||||
Non-terminal residue | 625 | ||||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
VWZR01007023 EMBL· GenBank· DDBJ | NXH70542.1 EMBL· GenBank· DDBJ | Genomic DNA |