A0A7K2TM37 · A0A7K2TM37_9ACTN

  • Protein
    Glutathione hydrolase proenzyme
  • Gene
    ggt
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Sulfur metabolism; glutathione metabolism.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site129L-glutamate (UniProtKB | ChEBI)
Active site427Nucleophile
Binding site469L-glutamate (UniProtKB | ChEBI)
Binding site493-494L-glutamate (UniProtKB | ChEBI)
Binding site516L-glutamate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionglutathione hydrolase activity
Molecular Functionleukotriene C4 gamma-glutamyl transferase activity
Biological Processglutathione biosynthetic process
Biological Processglutathione catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

Gene names

    • Name
      ggt
    • ORF names
      GTY84_31110

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • SID8352
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Kitasatosporales > Streptomycetaceae > Streptomyces

Accessions

  • Primary accession
    A0A7K2TM37

Proteomes

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-29
ChainPRO_503902791030-617Glutathione hydrolase proenzyme

Post-translational modification

Cleaved by autocatalysis into a large and a small subunit.

Keywords

Interaction

Subunit

This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

Family & Domains

Features

Showing features for region, compositional bias.

Type
IDPosition(s)Description
Region28-55Disordered
Compositional bias31-49Pro residues

Sequence similarities

Belongs to the gamma-glutamyltransferase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    617
  • Mass (Da)
    64,169
  • Last updated
    2021-04-07 v1
  • Checksum
    08B98404B159F742
MRRPVLRNVTLLAAAAVVASVGAAAPPTAARTGPAPIPAPAPAPAPARAATPAKTPVAVGHGGAVASVDADASAAGIEVLRNGGNAVDAAVATAAALGVTEPYSSGIGGGGYFVHYDARTRTVRTIDGRETAPLSADASLFTENGAPLPFDTAVTSGLAVGTPGTPATWQAALDRWGTRSLASVLKPAERLAQRGFTVDETFRSQTAANEERFRHFPDTARLFLPKGAPPAVGSTFRNPDLARTYRQLGREGVDAVYRGAIGKDIVATVNKPPTDPRSGWTARPGDLSAKDLKAYRAKVQAPTRTSYRGLGIYSIAPSSSGGTTVGEALNILERTDLARAGETRYLHRFIEASRVAFADRGRWVGDPGFEDVPVRELLSQRYADSRGCLIKDDAVLTSPLAPGDPRHPAPCARGGAAAPTTYEGENTTHLTVADRWGNVVSYTLTIEQTGGSGITVPGRGFLLNNELTDFSFAPASPAVHDPNLPGPGKRPRSSLAPTIVLNADDRPVLAVGSPGGATIITTVLQTLTGVLDRGLPLVDAIAAPRASQRNAARTELEPGLYDSAVRGRLEAIGHSFKLNPEIGAATGVQRLPDGRWLAAAEKVRRGGGSAMVVRPQR

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias31-49Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
WWGX01000104
EMBL· GenBank· DDBJ
MYU26130.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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