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A0A7J7U5V1 · A0A7J7U5V1_MYOMY

Function

function

Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Amine and polyamine biosynthesis; putrescine biosynthesis via L-ornithine pathway; putrescine from L-ornithine: step 1/1.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site360Proton donor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionornithine decarboxylase activity
Biological Processputrescine biosynthetic process from ornithine

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ornithine decarboxylase
  • EC number

Gene names

    • ORF names
      mMyoMyo1_014308

Organism names

  • Taxonomic identifier
  • Strain
    • MMyoMyo1
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Chiroptera > Yangochiroptera > Vespertilionidae > Myotis

Accessions

  • Primary accession
    A0A7J7U5V1

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue69N6-(pyridoxal phosphate)lysine

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain45-281Orn/DAP/Arg decarboxylase 2 N-terminal
Domain282-387Orn/DAP/Arg decarboxylase 2 C-terminal

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    462
  • Mass (Da)
    51,154
  • Last updated
    2021-04-07 v1
  • MD5 Checksum
    35AF063C615E0833E084063E3D81E897
MNSVSDEEFDCHFLDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSRTIVKTLAAIGTGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQIKYAASNGVQMMTFDSEVELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLLLERARELNIDVIGVSFHVGSGCTDPETFVQAISDARCVFDMGAEVGFNMYLLDIGGGFPGSEDAKLKFEEITSVINPALDRYFPSDSGVTVMAEPGRYYVASAFTLAVNIIAKKLVSKEQTGSDDEEESSEKTFMYYVNDGVYGSFNCILYDHAHVKPLLQKRPKPDEKYYSSSIWGPTCDGLDRIVERYGLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPTIYYVMSGPTWQLMQQIQNRDFPPEAEVEEDAGALPVSCAWESGMELLPAACASARVNV

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A7J7U623A0A7J7U623_MYOMYmMyoMyo1_014308464

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JABWUV010000014
EMBL· GenBank· DDBJ
KAF6308263.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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