A0A6J2PQ95 · A0A6J2PQ95_COTGO

Function

Catalytic activity

  • N2-(1-hydroxy-2-oxoethyl)-GDP + H2O = glycolate + GDP + H+
  • N2-(1-hydroxy-2-oxoethyl)-GMP + H2O = glycolate + GMP + H+
  • N2-(1-hydroxy-2-oxoethyl)-GTP + H2O = glycolate + GTP + H+
  • N2-(1-hydroxy-2-oxoethyl)-dGTP + H2O = dGTP + glycolate + H+
  • N2-(1-hydroxy-2-oxopropyl)-GDP + H2O = lactate + GDP + H+
  • N2-(1-hydroxy-2-oxopropyl)-GMP + H2O = lactate + GMP + H+
  • N2-(1-hydroxy-2-oxopropyl)-GTP + H2O = lactate + GTP + H+
  • N2-(1-hydroxy-2-oxopropyl)-dGTP + H2O = lactate + dGTP + H+
  • N6-(1-hydroxy-2-oxoethyl)-L-lysyl-[protein] + H2O = glycolate + L-lysyl-[protein] + H+
    EC:3.5.1.124 (UniProtKB | ENZYME | Rhea)
  • N6-(1-hydroxy-2-oxopropyl)-L-lysyl-[protein] + H2O = lactate + L-lysyl-[protein] + H+
    EC:3.5.1.124 (UniProtKB | ENZYME | Rhea)
  • N(omega)-(1-hydroxy-2-oxoethyl)-L-arginyl-[protein] + H2O = L-arginyl-[protein] + glycolate + H+
    EC:3.5.1.124 (UniProtKB | ENZYME | Rhea)
  • N(omega)-(1-hydroxy-2-oxopropyl)-L-arginyl-[protein] + H2O = lactate + L-arginyl-[protein] + H+
    EC:3.5.1.124 (UniProtKB | ENZYME | Rhea)
  • S-(1-hydroxy-2-oxoethyl)-L-cysteinyl-[protein] + H2O = glycolate + L-cysteinyl-[protein] + H+
    EC:3.5.1.124 (UniProtKB | ENZYME | Rhea)
  • S-(1-hydroxy-2-oxopropyl)-L-cysteinyl-[protein] + H2O = lactate + L-cysteinyl-[protein] + H+
    EC:3.5.1.124 (UniProtKB | ENZYME | Rhea)
  • an N2-(1-hydroxy-2-oxoethyl)-2'-deoxyguanosine in DNA + H2O = a 2'-deoxyguanosine in DNA + glycolate + H+
  • an N2-(1-hydroxy-2-oxoethyl)-guanosine in RNA + H2O = a guanosine in RNA + glycolate + H+
  • an N2-(1-hydroxy-2-oxopropyl)-2'-deoxyguanosine in DNA + H2O = a 2'-deoxyguanosine in DNA + lactate + H+
  • an N2-(1-hydroxy-2-oxopropyl)-guanosine in RNA + H2O = a guanosine in RNA + lactate + H+

GO annotations

AspectTerm
Cellular Componentmembrane raft
Cellular Componentmitochondrion
Cellular Componentnucleus
Molecular Functionoxidoreductase activity, acting on peroxide as acceptor
Molecular Functionprotein deglycase activity
Biological Processautophagy
Biological Processglycolate biosynthetic process
Biological Processglyoxal metabolic process
Biological Processresponse to oxidative stress
Biological Processsingle fertilization

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    protein deglycase
  • EC number
  • Alternative names
    • Maillard deglycase
    • Parkinsonism-associated deglycase

Gene names

    • Name
      park7

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Eupercaria > Perciformes > Notothenioidei > Bovichtidae > Cottoperca

Accessions

  • Primary accession
    A0A6J2PQ95

Proteomes

Subcellular Location

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-167DJ-1/PfpI

Sequence similarities

Belongs to the peptidase C56 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    175
  • Mass (Da)
    18,407
  • Last updated
    2020-10-07 v1
  • Checksum
    A9A41E809996BE4D
MAGKRALVILSKGAEEMETVIPVDIMRRAGIAVTVAGLTGTEPVQCSRNVIICPDASLEEASTQGPYDVVLLPGGMPGAQNLAESPAVKEVLKDQDSRKGLIAAICAGPTALLAHGIGYGSTVTTHPAMKEKMMAGDHYKYSEARVQKDGHYITSRGPGTSFEFALADCRRTYGG

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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