A0A4W5JY95 · A0A4W5JY95_9TELE
- ProteinInsulin-induced gene protein
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids242 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Mediates feedback control of cholesterol synthesis.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | SREBP-SCAP-Insig complex | |
Biological Process | cellular response to insulin stimulus | |
Biological Process | cholesterol biosynthetic process | |
Biological Process | SREBP signaling pathway | |
Biological Process | SREBP-SCAP complex retention in endoplasmic reticulum |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameInsulin-induced gene protein
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Protacanthopterygii > Salmoniformes > Salmonidae > Salmoninae > Hucho
Accessions
- Primary accessionA0A4W5JY95
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 36-57 | Helical | ||||
Sequence: LVIRGFMLFSIGVFLALVLNLL | ||||||
Transmembrane | 77-96 | Helical | ||||
Sequence: SAWWVPPCCGTASAIIGLLY | ||||||
Transmembrane | 139-156 | Helical | ||||
Sequence: VQLSLTLAALSIGLWWTF | ||||||
Transmembrane | 163-182 | Helical | ||||
Sequence: FGLGVVIALLATLSTQLLVY | ||||||
Transmembrane | 194-214 | Helical | ||||
Sequence: LYIRSWLPCIFFAGVITMGNI |
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length242
- Mass (Da)26,748
- Last updated2019-09-18 v1
- ChecksumF5CB0A958C8BE3C2
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A4W5JM59 | A0A4W5JM59_9TELE | 233 | |||
A0A4W5JJA8 | A0A4W5JJA8_9TELE | 233 | |||
A0A4W5JYC2 | A0A4W5JYC2_9TELE | 216 |
Keywords
- Technical term