A0A4W5JY95 · A0A4W5JY95_9TELE

  • Protein
    Insulin-induced gene protein
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Mediates feedback control of cholesterol synthesis.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentSREBP-SCAP-Insig complex
Biological Processcellular response to insulin stimulus
Biological Processcholesterol biosynthetic process
Biological ProcessSREBP signaling pathway
Biological ProcessSREBP-SCAP complex retention in endoplasmic reticulum

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Insulin-induced gene protein

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Protacanthopterygii > Salmoniformes > Salmonidae > Salmoninae > Hucho

Accessions

  • Primary accession
    A0A4W5JY95

Proteomes

Subcellular Location

Endoplasmic reticulum membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane36-57Helical
Transmembrane77-96Helical
Transmembrane139-156Helical
Transmembrane163-182Helical
Transmembrane194-214Helical

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-20Disordered

Sequence similarities

Belongs to the INSIG family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    242
  • Mass (Da)
    26,748
  • Last updated
    2019-09-18 v1
  • Checksum
    F5CB0A958C8BE3C2
MADSTVVSDQQRSGSGQTAPSRGPYIAVITNRSTTLVIRGFMLFSIGVFLALVLNLLQVQRNVTLFPPDVISSIFSSAWWVPPCCGTASAIIGLLYPCIDCRLGEPHKFKREWSSVMRCVAVFVGINHASAKVDFANNVQLSLTLAALSIGLWWTFDRSRSGFGLGVVIALLATLSTQLLVYNGVFQYTSPDFLYIRSWLPCIFFAGVITMGNIGRQLALCHRFINVLHTCMYTFIPTRAFY

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A4W5JM59A0A4W5JM59_9TELE233
A0A4W5JJA8A0A4W5JJA8_9TELE233
A0A4W5JYC2A0A4W5JYC2_9TELE216

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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