A0A4V3XBR4 · A0A4V3XBR4_9AGAM

  • Protein
    proteasome endopeptidase complex
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Cleavage of peptide bonds with very broad specificity.
    EC:3.4.25.1 (UniProtKB | ENZYME | Rhea)

Features

Showing features for active site.

116382004006008001,0001,2001,4001,600
TypeIDPosition(s)Description
Active site1417Nucleophile

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentmembrane
Cellular Componentnucleus
Cellular Componentproteasome core complex, beta-subunit complex
Molecular FunctionRNA nuclease activity
Molecular Functionthreonine-type endopeptidase activity
Biological Processproteolysis involved in protein catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    proteasome endopeptidase complex
  • EC number

Gene names

    • ORF names
      EW145_g6639

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DSM 108285
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Hymenochaetales > Hymenochaetaceae > Phellinidium

Accessions

  • Primary accession
    A0A4V3XBR4

Proteomes

Subcellular Location

Membrane
; Multi-pass membrane protein
Nucleus

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane12-35Helical
Transmembrane110-140Helical

Keywords

PTM/Processing

Keywords

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region207-367Disordered
Compositional bias222-251Polar residues
Compositional bias268-282Polar residues
Compositional bias326-343Basic and acidic residues
Region389-410Disordered
Region997-1024Disordered
Compositional bias1003-1017Acidic residues
Region1067-1088Disordered
Region1104-1124Disordered
Domain1169-1315PIN

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,638
  • Mass (Da)
    181,010
  • Last updated
    2019-07-31 v1
  • Checksum
    CDE78AF22FC38220
MPLAMDLLNFQGATAASTTAMLGAFYACAGIGLYLASIMEWMIGNTFPCVVFGTFASFPYDNTGGFWISYGIAIQPTFELAASFAPAGDASNSITAAAAGAMTREYNVGLGMYFCVWGILCAVYFLASLRTNVPFAIILLRQGHISLAAQEFRIAGGFAFVTALAGLWLDASMLCAAPSKPSRKGKEREPAQADLFYDRLIAIQRSKAGSSRPKEKSERPSTRTTSPIMQAASPPRRAQQPTPQVIISRSSPADSPDDFHRRRRPANTSSRVPSSSAHYTKAQGKLFNPDTDPVPMRRTAEPEVISENGSSSYAPRNGLPSPERGARHGRLFDYRKDDPVRFHVLKPTPPNGNRPTPTPKSSGEYVSASSTSSYAHSITSSNFTLNSTTDGSSASSALFDEQPREHASSSAFAQQLKKLYRGISNLESRLLREDGKDFSDETRVTLKRANEATAEPEEAEKDKWRKFVADHKQLSESMHNLLQLTLAPHVPASLRNIPTKYNIIIRLWTHAFNKPLESLRRASFHSAIALEHLQEFIIYAYTFYSMLLEEQTLEGFKSGWLEALGDLARYRMAIAAMTTPSNAHVAVGDFVPVNQQALAAQTQPDESMARIDDSPGPSVGVAAARALEVEPEKERWRNIARDWYAAGLADMPGTGKLHHHLGLLSRDVDKEELKSVYHFSKSMTTLHPFLTSRESVLQIWSVSAQTKRAIPDSRAADLFILLHGMLFTNVQLDDFPSTLARFMERLQLEGAEERDWIMMAVVNIAALLEYGKPTGFLRSTGGIGSGTTVGKEASSAAQAAAASAKVSMLAKRVDEMEVDDTEGIGMPPDIQPDSEDINMKVNGVLNVSPTLVHAQVAPSEQSEPLSFKYALQLTFEMFAFTLRTPTRKATPFSRPSLNPYNTVILTFLSTVMKHPAIQRAFERAIPWEDMVGFFCTIPRSSLAQVEGGIRLTSGCTPLPEDWCLRGMEWGGRRVFERGFWKSGEERHMEMEVLNTGEEKDGLTDGIIEDEDDEADGRQDASETSRRWVRIARAAGIFAKIIPGFHWEMGTRTFTVTNELEEKVKKWKEEDRLEREEEERRRSRRPWTSDDMDIDAEEDLFADELSEDDSGGSSDGEESEEVKSLKAKRRELLRLLRTTSKSPKRNTRPRRPRVSVAPRRSLLHVVPGYTVLVIDTNILLSSLSFVSSLVESMRWTVLVPLAVITELDGIAINVSPLGEAATAAITYISAHIRTHSLSLKVQTSRGNYLHDLNVRSEQIEFVAESWERSMDDLILRAMVWQDDHWIDRSSMLNAGNHDASGAAKVVLISFDRNLRLKARARQLDAADERDMAGILNSCDLLCMQRYSGYGSDYRQADNELEDDSFGGSMWGSSAGFGNLSKGVPTFNLPSLPDPTAFLRLHTDDHADPSCRIKIQHGTTTLAFRFKGGVIVAVDSRATAGSYIASGTVKKVIEINKFLLGTMAGGAADCQYWETYLGMRCRLHELRNHERISVAAASKYLSNLVSSYKGMGLSMGTMICGWDKTGPAVFYVDADGMRLKGDVFSVGSGSTIAYGVLDQGYHWDLSDEEAQELGRRSIYAAGHRDAYSGNSVNLYHVKEDGWKFIDNYDVSKLHYEGPGNVPGSTGGGYGYDVRIGVVQP

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias222-251Polar residues
Compositional bias268-282Polar residues
Compositional bias326-343Basic and acidic residues
Compositional bias1003-1017Acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SGPK01000525
EMBL· GenBank· DDBJ
THH02973.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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