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A0A4R5MHL2 · A0A4R5MHL2_9SPHI

Function

function

Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion.

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 2/4.
Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 3/4.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site50Zn2+ (UniProtKB | ChEBI); catalytic
Active site52Proton donor
Binding site83Zn2+ (UniProtKB | ChEBI); catalytic
Binding site92Zn2+ (UniProtKB | ChEBI); catalytic
Binding site162NADP+ (UniProtKB | ChEBI)
Binding site178NADP+ (UniProtKB | ChEBI)
Binding site192substrate
Binding site204NADP+ (UniProtKB | ChEBI)
Binding site208NADP+ (UniProtKB | ChEBI)
Binding site212substrate
Binding site215substrate
Binding site291substrate

GO annotations

AspectTerm
Molecular Function5-amino-6-(5-phosphoribosylamino)uracil reductase activity
Molecular Functiondiaminohydroxyphosphoribosylaminopyrimidine deaminase activity
Molecular Functionmetal ion binding
Biological Processriboflavin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Riboflavin biosynthesis protein RibD

Including 2 domains:

  • Recommended name
    Diaminohydroxyphosphoribosylaminopyrimidine deaminase
  • EC number
  • Short names
    DRAP deaminase
  • Alternative names
    • Riboflavin-specific deaminase
  • Recommended name
    5-amino-6-(5-phosphoribosylamino)uracil reductase
  • EC number
  • Alternative names
    • HTP reductase

Gene names

    • Name
      ribD
    • ORF names
      EZJ43_15675

Organism names

  • Taxonomic identifier
  • Strain
    • E01020
  • Taxonomic lineage
    Bacteria > Bacteroidota > Sphingobacteriia > Sphingobacteriales > Sphingobacteriaceae > Pedobacter

Accessions

  • Primary accession
    A0A4R5MHL2

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-131CMP/dCMP-type deaminase

Sequence similarities

In the C-terminal section; belongs to the HTP reductase family.
In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    348
  • Mass (Da)
    39,148
  • Last updated
    2019-07-31 v1
  • MD5 Checksum
    C351E5EF6404E998CAD4FED0CC7B7766
MVDEIYMNRCLELANLGSGNVSPNPMVGCVIVAGEQIIGEGYHRQYGQAHAEPNAVKAVFDRFGIDADSLLKKATAYVNLEPCAHFGKTPPCADLFVKHQLKKVVIGNTDPFSGVDGKGIEKLKNAGIEVITGVLKAECEYFNRRFFTRIKKQRPYIILKWAETANGYFGTTNGTQKWISGPLAKRLSHKWRTEEDAILVGKNTAMIDNPTLTARNWTGKNPTRLVIDKNLEIPTTHNMFNREAKTIIFNEVKTDVSENIHYIQMEDMHFYLPQKIAFQLYLMDIQSVIIEGGVSILNQFLDANLWDEARIFQSESNWSSGMKAPKINGFLTEAVQIGIDKLNLYANK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SJCY01000014
EMBL· GenBank· DDBJ
TDG35047.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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