A0A485PQ10 · A0A485PQ10_LYNPA
- ProteinSolute carrier family 22 member 2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids554 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- (R)-adrenaline(out) = (R)-adrenaline(in)
- (R)-noradrenaline(out) = (R)-noradrenaline(in)
- (R)-salsolinol(in) = (R)-salsolinol(out)
- 1-methylnicotinamide(out) = 1-methylnicotinamide(in)
- L-histidyl-L-proline diketopiperazine(in) = L-histidyl-L-proline diketopiperazine(out)
- N-methyl-(R)-salsolinol(in) = N-methyl-(R)-salsolinol(out)
- acetylcholine(in) = acetylcholine(out)
- agmatine(out) = agmatine(in)This reaction proceeds in the forward and the backward directions.
- choline(out) = choline(in)
- creatinine(in) = creatinine(out)
- dopamine(out) = dopamine(in)
- guanidine(out) = guanidine(in)
- histamine(out) = histamine(in)
- prostaglandin E2(out) = prostaglandin E2(in)
- prostaglandin F2alpha(out) = prostaglandin F2alpha(in)
- putrescine(out) = putrescine(in)
- serotonin(out) = serotonin(in)
- spermidine(in) = spermidine(out)
- thiamine(in) = thiamine(out)
- tyramine(in) = tyramine(out)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | basolateral plasma membrane | |
Cellular Component | lateral plasma membrane | |
Molecular Function | organic cation transmembrane transporter activity | |
Biological Process | monoatomic ion transport |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameSolute carrier family 22 member 2
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Feliformia > Felidae > Felinae > Lynx
Accessions
- Primary accessionA0A485PQ10
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Basal cell membrane ; Multi-pass membrane protein
Basolateral cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 21-44 | Helical | |||
Transmembrane | 150-170 | Helical | |||
Transmembrane | 177-195 | Helical | |||
Transmembrane | 201-224 | Helical | |||
Transmembrane | 236-257 | Helical | |||
Transmembrane | 263-282 | Helical | |||
Transmembrane | 349-367 | Helical | |||
Transmembrane | 379-397 | Helical | |||
Transmembrane | 404-423 | Helical | |||
Transmembrane | 429-452 | Helical | |||
Transmembrane | 464-484 | Helical | |||
Transmembrane | 496-513 | Helical | |||
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 100-518 | Major facilitator superfamily (MFS) profile | |||
Sequence similarities
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length554
- Mass (Da)61,926
- Last updated2019-06-05 v1
- MD5 Checksum095D95D7FBFF6CAC4AA54AE53F97C229
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CAAGRJ010038049 EMBL· GenBank· DDBJ | VFV45736.1 EMBL· GenBank· DDBJ | Genomic DNA |