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A0A485NVL8 · A0A485NVL8_LYNPA

Function

Catalytic activity

  • (9Z)-octadecenoyl-sn-glycero-3-phosphate + H2O = (9Z-octadecenoyl)-glycerol + phosphate
    This reaction proceeds in the forward direction.
  • 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + phosphate
    This reaction proceeds in the forward direction.
  • 1,2-dihexadecanoyl-sn-glycero-3-phosphate + H2O = 1,2-dihexadecanoyl-sn-glycerol + phosphate
    This reaction proceeds in the forward direction.
  • 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1-(9Z-octadecenoyl)-sn-glycerol + phosphate
    This reaction proceeds in the forward direction.
  • 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + phosphate
    This reaction proceeds in the forward direction.
  • N-(9Z-octadecenoyl)-ethanolamine phosphate + H2O = N-(9Z-octadecenoyl) ethanolamine + phosphate
    This reaction proceeds in the forward direction.
  • N-(octanoyl)-sphing-4-enine-1-phosphate + H2O = N-octanoylsphing-4-enine + phosphate
    This reaction proceeds in the forward direction.
  • a monoacyl-sn-glycero-3-phosphate + H2O = a monoacylglycerol + phosphate
    This reaction proceeds in the forward direction.
  • sphing-4-enine 1-phosphate + H2O = sphing-4-enine + phosphate
    This reaction proceeds in the forward direction.
  • a 1,2-diacyl-sn-glycero-3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate
    This reaction proceeds in the forward direction.
    EC:3.1.3.4 (UniProtKB | ENZYME | Rhea)
  • a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + phosphate + H+
    This reaction proceeds in the forward direction.
    EC:3.6.1.75 (UniProtKB | ENZYME | Rhea)
  • a 1-acyl-sn-glycero-3-phosphate + H2O = a 1-acyl-sn-glycerol + phosphate
    This reaction proceeds in the forward direction.
    EC:3.1.3.106 (UniProtKB | ENZYME | Rhea)
  • an N-acylsphing-4-enine 1-phosphate + H2O = an N-acylsphing-4-enine + phosphate
    This reaction proceeds in the forward direction.

Pathway

Lipid metabolism; phospholipid metabolism.
Phospholipid metabolism.

GO annotations

AspectTerm
Cellular Componentapical plasma membrane
Cellular Componentcaveola
Molecular Functionlysophosphatidic acid phosphatase activity
Molecular Functionphosphatidate phosphatase activity
Biological Processphospholipid dephosphorylation
Biological Processphospholipid metabolic process
Biological Processsignal transduction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phospholipid phosphatase 1
  • EC number
  • Alternative names
    • Lipid phosphate phosphohydrolase 1
    • PAP2-alpha
    • Phosphatidate phosphohydrolase type 2a
    • Phosphatidic acid phosphatase 2a

Gene names

    • ORF names
      LYPA_23C007398

Organism names

Accessions

  • Primary accession
    A0A485NVL8

Proteomes

Subcellular Location

Apical cell membrane
; Multi-pass membrane protein
Membrane raft
; Multi-pass membrane protein
Membrane, caveola
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane38-61Helical
Transmembrane73-91Helical
Transmembrane145-165Helical
Transmembrane177-196Helical
Transmembrane208-230Helical

Keywords

PTM/Processing

Keywords

Interaction

Subunit

Forms functional homodimers and homooligomers that are not required for substrate recognition and catalytic activity. Can also form heterooligomers with PLPP2 and PLPP3.

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain82-223Phosphatidic acid phosphatase type 2/haloperoxidase
Region240-265Disordered
Compositional bias250-265Polar residues

Sequence similarities

Belongs to the PA-phosphatase related phosphoesterase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    265
  • Mass (Da)
    29,979
  • Last updated
    2019-06-05 v1
  • MD5 Checksum
    9EE249A76EA2440FB52156F46C31BB7D
MPMAVLNLGQIYPFQRGFFCKDNSIQYPYHDSTVTSTVLNIVGLGLPISSMIVGEALSVYYNLLHSNSFIRNNYIATIYKAIGTFLFGAAASQSLTDIAKYSIGRLRPHFLDVCDPDWSKINCSAGYIENYICRGNAQKVKEGRLSFYSGHSSFSMYCMLFVALYLQARMKGDWARLLRPTLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVAILVVVYVSDFFRERNSPFKERKEEDSHTTLHETPTASNHYRNNHQP

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A485NPG1A0A485NPG1_LYNPALYPA_23C007398215

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias250-265Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CAAGRJ010019206
EMBL· GenBank· DDBJ
VFV34092.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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