A0A485MA61 · A0A485MA61_LYNPA
- ProteinLarge neutral amino acids transporter small subunit 2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids492 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- 3,3',5-triiodo-L-thyronine(out) = 3,3',5-triiodo-L-thyronine(in)This reaction proceeds in the forward direction.
- 3,3'-diiodo-L-thyronine(out) = 3,3'-diiodo-L-thyronine(in)This reaction proceeds in the forward direction.
- L-phenylalanine(out) + L-alanine(in) = L-phenylalanine(in) + L-alanine(out)
- L-cysteine(in) + L-phenylalanine(out) = L-cysteine(out) + L-phenylalanine(in)
- L-cysteine(out) + L-methionine(in) = L-cysteine(in) + L-methionine(out)
- L-dopa(out) + L-phenylalanine(in) = L-dopa(in) + L-phenylalanine(out)
- L-phenylalanine(out) + L-glutamine(in) = L-phenylalanine(in) + L-glutamine(out)
- L-histidine(in) + L-phenylalanine(out) = L-histidine(out) + L-phenylalanine(in)
- L-isoleucine(in) + L-phenylalanine(out) = L-isoleucine(out) + L-phenylalanine(in)
- L-leucine(in) + L-phenylalanine(out) = L-leucine(out) + L-phenylalanine(in)
- L-leucine(out) + L-methionine(in) = L-leucine(in) + L-methionine(out)
- S-methylmercury-L-cysteine(in) + L-leucine(out) = S-methylmercury-L-cysteine(out) + L-leucine(in)
- L-phenylalanine(out) + L-methionine(in) = L-phenylalanine(in) + L-methionine(out)
- S-methylmercury-L-cysteine(out) + L-methionine(in) = S-methylmercury-L-cysteine(in) + L-methionine(out)
- L-serine(in) + L-phenylalanine(out) = L-serine(out) + L-phenylalanine(in)
- L-tryptophan(in) + L-phenylalanine(out) = L-tryptophan(out) + L-phenylalanine(in)
- L-valine(in) + L-phenylalanine(out) = L-valine(out) + L-phenylalanine(in)
- S-methylmercury-L-cysteine(in) + L-phenylalanine(out) = S-methylmercury-L-cysteine(out) + L-phenylalanine(in)
- L-phenylalanine(out) + glycine(in) = L-phenylalanine(in) + glycine(out)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | basolateral plasma membrane | |
Cellular Component | lateral plasma membrane | |
Molecular Function | antiporter activity | |
Molecular Function | L-amino acid transmembrane transporter activity | |
Molecular Function | neutral L-amino acid transmembrane transporter activity |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameLarge neutral amino acids transporter small subunit 2
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Feliformia > Felidae > Felinae > Lynx
Accessions
- Primary accessionA0A485MA61
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Basolateral cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 43-63 | Helical | |||
Transmembrane | 75-96 | Helical | |||
Transmembrane | 116-134 | Helical | |||
Transmembrane | 162-180 | Helical | |||
Transmembrane | 192-212 | Helical | |||
Transmembrane | 232-251 | Helical | |||
Transmembrane | 272-293 | Helical | |||
Transmembrane | 313-333 | Helical | |||
Transmembrane | 365-384 | Helical | |||
Transmembrane | 390-414 | Helical | |||
Transmembrane | 426-447 | Helical | |||
Transmembrane | 453-472 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-18 | Basic and acidic residues | |||
Region | 1-35 | Disordered | |||
Sequence similarities
Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length492
- Mass (Da)53,441
- Last updated2019-06-05 v1
- MD5 Checksum9AAA91E7A0799D16F8F70FE49880A4BC
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A485MBU6 | A0A485MBU6_LYNPA | LYPA_23C022372 | 537 | ||
A0A485MDM9 | A0A485MDM9_LYNPA | LYPA_23C022372 | 331 | ||
A0A485MCT7 | A0A485MCT7_LYNPA | LYPA_23C022372 | 418 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-18 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CAAGRJ010000170 EMBL· GenBank· DDBJ | VFV17675.1 EMBL· GenBank· DDBJ | Genomic DNA |