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A0A3C1T1Z2 · A0A3C1T1Z2_9BACT

Function

function

Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; L-lysine from DL-2,6-diaminopimelate: step 1/1.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site221pyridoxal 5'-phosphate (UniProtKB | ChEBI)
Binding site301substrate
Binding site305substrate
Active site331Proton donor
Binding site332substrate
Binding site359pyridoxal 5'-phosphate (UniProtKB | ChEBI)
Binding site359substrate

GO annotations

AspectTerm
Molecular Functiondiaminopimelate decarboxylase activity
Molecular Functionpyridoxal phosphate binding
Biological Processlysine biosynthetic process via diaminopimelate

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Diaminopimelate decarboxylase
  • EC number
  • Short names
    DAP decarboxylase
    ; DAPDC

Gene names

    • Name
      lysA
    • ORF names
      DCQ97_00945

Organism names

Accessions

  • Primary accession
    A0A3C1T1Z2

Proteomes

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue51N6-(pyridoxal phosphate)lysine

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain27-269Orn/DAP/Arg decarboxylase 2 N-terminal
Domain270-357Orn/DAP/Arg decarboxylase 2 C-terminal

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    409
  • Mass (Da)
    45,754
  • Last updated
    2019-01-16 v1
  • MD5 Checksum
    259649346411EA9C7BFFAAC41435D72C
MSLLSQQELRSLAHEYGTPLYVYDAATITGQYKKLSSAFAETDTRFFYACKALTNIQVLKHINGLGCSVDCSSINEVKLALRAGFDPGNILYTSNGIHFSEIEEAQGLGVHINIDSLSNLEKFGRKFGHSYPVGIRLRPNIMGGGNLKVSTGHDKSKFGIPVDQLDKILTLVSTHNLYIQNLHIHTGSDIKDVDTFIKGIDVLFDIIPSFHELDSIDLGGGFKVPYQEGDAETDIPLLAKKVKEAFDNHPNSDGRHLQVWFEPGKFLVSAAGYLVTEVNVLKETSATTFAGVNSGFNHLIRPMFYEAYHRIENISNPTGVQKEYSVVGNICETDTFAWDRKLNEVREGDLLVFYNAGAYGFEMSSNFNSRFKPAEVLVENGKARLIRRRDEFEDLLRNQVINQELKMKN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DMRT01000024
EMBL· GenBank· DDBJ
HAO45461.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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