A0A372GHA1 · A0A372GHA1_9ACTN

  • Protein
    Phosphoserine aminotransferase
  • Gene
    serC
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Note: Binds 1 pyridoxal phosphate per subunit.

Pathway

Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.
Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 3/5.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site50L-glutamate (UniProtKB | ChEBI)
Binding site108pyridoxal 5'-phosphate (UniProtKB | ChEBI)
Binding site154pyridoxal 5'-phosphate (UniProtKB | ChEBI)
Binding site178pyridoxal 5'-phosphate (UniProtKB | ChEBI)
Binding site201pyridoxal 5'-phosphate (UniProtKB | ChEBI)
Binding site253-254pyridoxal 5'-phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentperoxisome
Molecular Functionalanine-glyoxylate transaminase activity
Molecular FunctionO-phospho-L-serine:2-oxoglutarate aminotransferase activity
Molecular Functionpyridoxal phosphate binding
Molecular Functionserine-pyruvate transaminase activity
Biological Processglycine biosynthetic process, by transamination of glyoxylate
Biological ProcessL-serine biosynthetic process
Biological Processpyridoxine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoserine aminotransferase
  • EC number
  • Alternative names
    • Phosphohydroxythreonine aminotransferase
      (PSAT
      )

Gene names

    • Name
      serC
    • ORF names
      D0T12_12905

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • LHW52907
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Streptosporangiales > Thermomonosporaceae > Actinomadura

Accessions

  • Primary accession
    A0A372GHA1

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue202N6-(pyridoxal phosphate)lysine

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain140-337Aminotransferase class V

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    378
  • Mass (Da)
    40,589
  • Last updated
    2018-11-07 v1
  • Checksum
    9B9F0025B28CAE71
MTESANPTIDIPADIRPADGRFGCGPSKVRPEQLAALAESGSTYMGTSHRQKPVKSLVGRVREGLSQLFSLPDGYEVVLGNGGTTAFWDAAAFGLVRQRSQHLTFGEFSSKFAKVTTTAPWLGEPTVITGPPGTHPEASAEEDVDVYALTHNETSTGVAMRIARPAGTTAREGLVLVDATSGAGGLPVDVSETDVYYFAPQKCFAADGGLWVALASPAALERIDEIANSDRYVPEFLNLKTAVDNSAKDQTYNTPAVATLLLFAEQIEWMNSRGGLAWTTARTADSSQRLYTWAEKTSYTTPFVVDPAQRSQVVGTIDFNDDVDAAAVAKTLRANGIVDTEPYRKLGRNQLRIGMFPAIDPDDVEALTACVDHVVERL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
QVNQ01000004
EMBL· GenBank· DDBJ
RFS84473.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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