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A0A371IQ77 · A0A371IQ77_9FIRM

Function

function

Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionpenicillin binding
Molecular Functionpeptidoglycan glycosyltransferase activity
Molecular Functionserine-type D-Ala-D-Ala carboxypeptidase activity
Biological Processpeptidoglycan biosynthetic process
Biological Processproteolysis
Biological Processresponse to antibiotic

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Penicillin-binding protein 1A
  • EC number

Gene names

    • ORF names
      CHF27_012465

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CCRI-22766
  • Taxonomic lineage
    Bacteria > Bacillota > Clostridia > Peptostreptococcales > Peptostreptococcaceae > Romboutsia

Accessions

  • Primary accession
    A0A371IQ77

Proteomes

Subcellular Location

Cell membrane
; Single-pass type II membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane80-105Helical

Keywords

  • Cellular component

Family & Domains

Features

Showing features for compositional bias, region, domain.

Type
IDPosition(s)Description
Compositional bias1-68Polar residues
Region1-73Disordered
Domain134-291Glycosyl transferase family 51
Domain479-741Penicillin-binding protein transpeptidase
Region820-914Disordered
Compositional bias832-851Basic and acidic residues
Compositional bias855-881Polar residues
Compositional bias895-914Polar residues

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    914
  • Mass (Da)
    98,750
  • Last updated
    2018-11-07 v1
  • MD5 Checksum
    F1C66C557BD727D96EBA0F28D1CA38B8
MTNDNNKNGNKIRRRQVSPSTNKTSSTTRPNPNRSSNVNRSNTSNRPNSSNKPSSSSRSSSTSTKKISNSNKKKQDKFKFLRVAGTVFLVLLVVGAAAGTGLAFASLRDVSPVTKALLDEKTYQTTKIYYSNGNLLSNAPSINKKEPVKLDKINSNLKNAVISIEDERFYEHKGVDLVGLARSVVKTLMGTKQGGSTIPMQVSKMLLTSTEQSIPRKIKDIYYAYEMSKNLSKDEILESYLNNFFVGKGLIGAEAGARGYFDKSASELKLEEAALLAGSTKNPSSYSAYVTSKLDGTESKSDLESKLLFFANTNDDNFDDPTDADFILVDKLESWGLVHDKDTYKQLKAGTMVVRKAVNNPKAKKRQEVVLKKMLELGYITQEEHDKAVAAPINIKLPKSSEKVATSVEDLIEYDVIDALMAQGNTKDEAYNMFYSGGLKINTTIDPNMQDTLEKQYDDNRNFPGHTVGPDGISQPQSSMVILDYRTGQIKALVGGRHVTGRKTLNRATYPQQPGSTIKPLSVYTPAIDTLKITQANSASDAKGGYKFSKNNKWNPNTTTAGYGSMSLRKALAYSSNTIAVKTAEMLGGSYEECVDIMIDYLKNFGISTVVDNKTEKEDKTDRRFPSLTLGGMTKGVSPLEMAAAYGTLANGGVYVEPTIFTTITSYDKQLIVKTTPEEHKVIDPEVAYVITDMLHSVITEGIGGSAAIGNEMPVAGKTGTTNEGLDVWFVGYTPYYVGATYIGDDAGRKDPSTGTTISRRTVAGGSTTAARLWSKVMTDVHKNLTVTKFKVPSNIYFNKINLIDGGFSSGGSSAAFIKGTAPTKASSHSSVQQHPKKEESNTEEAPASQKPEEKPSTPPDNGGNTTQPDNNNTSGNGANAIPTPTPPPTDTGTTTPPDTGGSATTPPAQQPAQ

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-68Polar residues
Compositional bias832-851Basic and acidic residues
Compositional bias855-881Polar residues
Compositional bias895-914Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NOJZ02000035
EMBL· GenBank· DDBJ
RDY22622.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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