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A0A345D690 · A0A345D690_ARAMA

  • Protein
    NADH-ubiquinone oxidoreductase chain 4
  • Gene
    ND4
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial membrane
Cellular Componentrespiratory chain complex I
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Molecular Functionubiquinone binding
Biological ProcessATP synthesis coupled electron transport
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 4
  • EC number

Gene names

    • Name
      ND4

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • PA59
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Telluraves > Australaves > Psittaciformes > Psittacidae > Ara

Accessions

  • Primary accession
    A0A345D690

Subcellular Location

Mitochondrion membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane116-133Helical
Transmembrane145-167Helical
Transmembrane197-218Helical
Transmembrane230-250Helical
Transmembrane262-283Helical
Transmembrane290-310Helical
Transmembrane316-334Helical
Transmembrane346-366Helical
Transmembrane397-419Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-17
ChainPRO_501672432118-464NADH-ubiquinone oxidoreductase chain 4

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-109NADH:ubiquinone oxidoreductase chain 4 N-terminal
Domain113-404NADH:quinone oxidoreductase/Mrp antiporter membrane subunit

Sequence similarities

Belongs to the complex I subunit 4 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    464
  • Mass (Da)
    51,610
  • Last updated
    2018-11-07 v1
  • MD5 Checksum
    698A6AC44C6C025F76799EF8B8C5D7D0
MLKIILPTLMLLPTTLLSPPKLMWTNTTMHSLLIATLSLQWLAPSYYPYKNLAQYMGIDQTSSPLLVLSCWLTPLMILASQGHLQHEPSARKQIFTMTLVTVQPLIILAFSTTELMMFYISFEATLIPTLILITRWGSQPERLSAGIYLLFXTLISSLPLLVAILYLHTQMGTLHFPTLKLHTHIPQPTSTEYWSPLLXNIALLMAFMVKAPLYXLXLXXXXXXXXXXXXXXXXXAALLLKLGGYGIMRITCLTSPPTNNLLHYPFIALALWGALMTSSICLRQIDLKSLIAYSSVSHMGLVIAACMIQTHWSFSGAMILMISHGLTSSMLFCLANTNYERTXSRILLLTRGLQPLLPLMATWWLLANLTNMGLPPTTNLMAELSXMXTLFNWSPPTIILTGAAILLTASYTLSMLTTTQRGTLPSHITTLQSSTTREHLLMILHLLPTLLLILKPELISGPLS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MH400237
EMBL· GenBank· DDBJ
AXF83870.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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